AB1248

Sigma-Aldrich

Anti-Cytochrome P450 Enzyme CYP1A2 Antibody

serum, Chemicon®

eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

application(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Specificity

Reacts with human cytochrome P450 enzyme CYP1A2 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes. By Western blot the antibody recognizes a protein with a molecular weight of approximately 54 kDa.

Immunogen

Synthetic peptide

Application

Anti-Cytochrome P450 Enzyme CYP1A2 Antibody is an antibody against Cytochrome P450 Enzyme CYP1A2 for use in IH & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
Western blot: 1:1,000-1:4,000

Immunohistochemistry on frozen and formaldehyde treated sections.

Optimal working dilutions must be determined by end user.

Linkage

Replaces: MAB3526

Physical form

Rabbit antiserum. Liquid. No preservatives

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Patricia Prieto et al.
Frontiers in physiology, 7, 548-548 (2016-12-03)
Stem cell therapy has emerged as a promising new area in regenerative medicine allowing the recovery of viable tissues. Among the many sources of adult stem cells, bone marrow-derived are easy to expand in culture via plastic adherence and their...
D R Nelson et al.
DNA and cell biology, 12(1), 1-51 (1993-01-01)
We provide here a list of 221 P450 genes and 12 putative pseudogenes that have been characterized as of December 14, 1992. These genes have been described in 31 eukaryotes (including 11 mammalian and 3 plant species) and 11 prokaryotes....
Short synthetic peptides exploited for reliable and specific targeting of antibodies to the C-termini of cytochrome P450 enzymes.
Edwards, R J, et al.
Biochemical Pharmacology, 49, 39-47 (1995)
P-450 cytochromes: structure and function.
Black, S D and Coon, M J
Advances in Enzymology and Related Areas of Molecular Biology, 60, 35-87 (1987)
P E Thomas et al.
Federation proceedings, 46(8), 2563-2566 (1987-06-01)
Cytochrome P-450 is the terminal oxidase of an electron transport system that is responsible for the oxidative metabolism of a large variety of endogenous and exogenous compounds. This broad substrate selectivity is caused by multiple isozymes of cytochrome P-450 and...

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