AB3421

Anti-Complement C3 Antibody

Name: Anti-Complement C3 Antibody
Brand: MM
Price: 564 USD

Chemicon^®, from chicken

Synonym(s):

Anti-AHUS5, Anti-ARMD9, Anti-ASP, Anti-C3a, Anti-C3b, Anti-CPAMD1, Anti-HEL-S-62p

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100 μG

$564.00

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Key Documents

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Product Name

Anti-Complement C3 Antibody, Chemicon^®, from chicken

biological source

chicken

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable

NCBI accession no.

NM_000064.2

UniProt accession no.

P01024

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... C3(718)

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This Item	GW20073F	SAB1403622	MABF972
Sigma-Aldrich AB3421 Anti-Complement C3 Antibody	Sigma-Aldrich GW20073F Anti-Complement C3 antibody produced in chicken	Sigma-Aldrich SAB1403622 Monoclonal Anti-C3 antibody produced in mouse	Sigma-Aldrich MABF972 Anti-Complement C3b/iC3b Antibody, clone 3E7, neutralizing
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
antibody form affinity purified immunoglobulin	antibody form affinity isolated antibody	antibody form ascites fluid	antibody form purified immunoglobulin
biological source chicken	biological source chicken	biological source mouse	biological source mouse
clone polyclonal	clone polyclonal	clone 5F9, monoclonal	clone 3E7, monoclonal
shipped in wet ice	shipped in wet ice	shipped in dry ice	shipped in wet ice
UniProt accession no. P01024	UniProt accession no. P01024	UniProt accession no. P01024	UniProt accession no. P01024

Application

Detect Complement C3 using this Anti-Complement C3 Antibody validated for use in ELISA.

ELISA, direct: 0.1 μg/mL

It is expected that the antibody will also work for Western blot, immunohistochemistry and immunocytochemistry. Specific reactivity has not been confirmed.

Optimal working dilutions must be determined by the end user.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Biochem/physiol Actions

Complement C3

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Human C3, full length plasma protein.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Chicken IgY fraction, in 0.15 M NaCl, 0.02 M NaH2PO4, 0.1% NaN3, pH 7.2.

Preparation Note

Maintain at 2-8*C in undiluted aliquots up to 6 months after date of receipt.
Avoid freezing temperatures.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Estrogen promotes innate immune evasion of Candida albicans through inactivation of the alternative complement system.

Pizga Kumwenda et al.

Cell reports, 38(1), 110183-110183 (2022-01-06)

Candida albicans is a commensal of the urogenital tract and the predominant cause of vulvovaginal candidiasis (VVC). Factors that increase circulatory estrogen levels such as pregnancy, the use of oral contraceptives, and hormone replacement therapy predispose women to VVC, but

The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders.

Kelsey B Law et al.

Autophagy, 13(5), 868-884 (2017-05-20)

Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal

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