MAB1962Z

Anti-Integrin β2 Antibody, clone P4H9, azide free

Name: Anti-Integrin β2 Antibody, clone P4H9, azide free
Brand: MM
Price: 534 USD

clone P4H9, Chemicon^®, from mouse

Synonym(s):

CD18, MAB1962

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100 μG

$534.00

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Key Documents

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

P4H9, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

immunohistochemistry: suitable

isotype

IgG3

NCBI accession no.

NM_000211.2

UniProt accession no.

P05107

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB2(3689)

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This Item	MAB1962	CBL158	MAB1950Z
Sigma-Aldrich MAB1962Z Anti-Integrin β2 Antibody, clone P4H9, azide free	Sigma-Aldrich MAB1962 Anti-Integrin β2 Antibody, clone P4H9	Sigma-Aldrich CBL158 Anti-Integrin β2 [CD18] Antibody	Sigma-Aldrich MAB1950Z Anti-Integrin α2 Antibody, clone P1E6, azide free
Gene Information human ... ITGB2(3689)	Gene Information human ... ITGB2(3689)	Gene Information human ... ITGB2(3689)	Gene Information human ... ITGA2(3673)
clone P4H9, monoclonal	clone P4H9, monoclonal	clone MEM 48, monoclonal	clone P1E6, monoclonal
biological source mouse	biological source mouse	biological source mouse	biological source mouse
antibody form purified antibody	antibody form purified antibody	antibody form purified antibody	antibody form purified immunoglobulin
species reactivity human	species reactivity human	species reactivity human	species reactivity human
technique(s) immunohistochemistry: suitable	technique(s) immunohistochemistry: suitable	technique(s) flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable	technique(s) immunocytochemistry: suitable, immunohistochemistry: suitable

Application

Anti-Integrin β2 Antibody, clone P4H9, azide free detects level of Integrin β2 & has been published & validated for use in IH.

Research Category
Cell Structure

Research Sub Category
Integrins

Suitable for use in immunofluorescence.

Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.

For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.

Biochem/physiol Actions

beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.

Physical form

Format: Purified

Sterile-filtered liquid containing no preservatives.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Exosomes derived from human macrophages suppress endothelial cell migration by controlling integrin trafficking.

Hee Doo Lee et al.

European journal of immunology, 44(4), 1156-1169 (2013-12-18)

Integrin trafficking, including internalization, recycling, and lysosomal degradation, is crucial for the regulation of cellular functions. Exosomes, nano-sized extracellular vesicles, are believed to play important roles in intercellular communications. This study demonstrates that exosomes released from human macrophages negatively regulate

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.

Vira V Artym et al.

The Journal of cell biology, 208(3), 331-350 (2015-02-04)

Cell interactions with the extracellular matrix (ECM) can regulate multiple cellular activities and the matrix itself in dynamic, bidirectional processes. One such process is local proteolytic modification of the ECM. Invadopodia of tumor cells are actin-rich proteolytic protrusions that locally

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