06206

Octanoyl-L-carnitine

analytical standard

• Synonym(s): (2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxooctyl)oxy]-1-propanaminium inner salt, L-Carnitine octanoyl ester, C8-Carnitine
• Empirical Formula (Hill Notation): C₁₅H₂₉NO₄
• CAS Number: 25243-95-2
• Molecular Weight: 287.40
• UNSPSC Code: 41116107
• NACRES: NB.21
• Beilstein/REAXYS Number: 5955761

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥97.0% (HPLC)
• optical activity: [α]/D -17±2°, c = 0.1 in H₂O
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤10% water
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCCCCC)=O)CC([O-])=O
• InChI: 1S/C15H29NO4/c1-5-6-7-8-9-10-15(19)20-13(11-14(17)18)12-16(2,3)4/h13H,5-12H2,1-4H3/t13-/m1/s1
• InChI key: CXTATJFJDMJMIY-CYBMUJFWSA-N

Description

General description

Octanoyl-L-carnitine is a medium-chain endogenous ester of L-carnitine, obtained via acylcarnitine family transferase.

Application

Octanoyl-L-carnitine may be used as an analytical standard in the following:

• Separation and identification of underivatized octanoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).[1]
• Quantification of the analyte in biological samples of patients treated with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS). The feasibility of adding L-carnitine to the peritoneal dialysis (PD) solution in APD-treated end-stage renal disease patients is investigated.

It may be used as a test material for investigating its rate of oxidation by mitochondria, isolated from the livers of fed, starved and glucagon treated virgin and lactating rats.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable