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MilliporeSigma

46923

Testosterone

VETRANAL®, analytical standard

Synonym(s):

17β-Hydroxy-3-oxo-4-androstene, 17β-Hydroxy-4-androsten-3-one, 4-Androsten-17β-ol-3-one, trans-Testosterone

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250 MG

$466.50

$466.50

List Price$622.00Save 25%

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About This Item

Empirical Formula (Hill Notation):
C19H28O2
CAS Number:
Molecular Weight:
288.42
Beilstein/REAXYS Number:
1915399
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

H2O: soluble

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChI key

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Gene Information

human ... AR(367)

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This Item
BP1076PHR2027T1500
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical

application(s)

-

format

neat

format

neat

format

neat

format

-

Quality Level

100

Quality Level

-

Quality Level

300

Quality Level

200

grade

analytical standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges


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Y Zimmerman et al.
Human reproduction update, 20(1), 76-105 (2013-10-02)
BACKGROUND; Combined oral contraceptives (COCs) reduce levels of androgen, especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by increasing levels of sex hormone-binding globulin (SHBG). Although this suppressive effect has been investigated by numerous studies over many
E David Crawford et al.
Urology, 83(5), 1122-1128 (2014-03-26)
To demonstrate the safety and efficacy of up to 5 years of degarelix treatment and the effects of crossing over from leuprolide to degarelix in the extension phase of a phase III pivotal 1-year trial. Patients receiving degarelix who completed
Yasushi Totoki et al.
Nature genetics, 46(12), 1267-1273 (2014-11-05)
Diverse epidemiological factors are associated with hepatocellular carcinoma (HCC) prevalence in different populations. However, the global landscape of the genetic changes in HCC genomes underpinning different epidemiological and ancestral backgrounds still remains uncharted. Here a collection of data from 503
Franck Oury et al.
The Journal of clinical investigation, 123(6), 2421-2433 (2013-06-04)
The osteoblast-derived hormone osteocalcin promotes testosterone biosynthesis in the mouse testis by binding to GPRC6A in Leydig cells. Interestingly, Osteocalcin-deficient mice exhibit increased levels of luteinizing hormone (LH), a pituitary hormone that regulates sex steroid synthesis in the testes. These
Tracey Bridger et al.
Archives of pediatrics & adolescent medicine, 160(3), 241-246 (2006-03-08)
To determine whether metformin or placebo could, in conjunction with healthy lifestyle counseling, decrease serum testosterone levels and related aberrations in adolescents with hyperandrogenism, hyperinsulinemia, and polycystic ovarian syndrome. Randomized, placebo-controlled, double-blind trial. Pediatric university teaching hospital. Twenty-two adolescents aged

Articles

Los sistemas de producción de agua ultrapura Milli-Q® suministran agua exenta de contaminantes orgánicos, incluidas las hormonas presentes en el agua del grifo de un laboratorio, lo que los hace adecuados para los análisis mediante LC-MS/MS más sensibles.

Milli-Q® ultrapure water systems deliver water free of organic contaminants , including hormones present in a lab's tap water, making it suitable for the most sensitive LC-MS/MS analyses.

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