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PHR1309

Dimethyl Sulfoxide

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Sulfoxide, DMSO

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Size/SKUAvailabilityPrice
3 g

Available to ship TODAYfromMILWAUKEE

$115.00

About This Item

CAS Number:
UNSPSC Code:
41116107
EC Number:
200-664-3
NACRES:
NA.24

$115.00


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Quality Segment

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. D2050000, traceable to USP 1211006

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[S](=O)(C)C

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
Dimethyl Sulfoxide (DMSO) is an amphipathic molecule and contains both highly polar and apolar groups, making it an efficient solvent as it can dissolve in both aqueous and organic solvents. It has its therapeutic use in the treatment of a variety of human conditions such as brain edema, amyloidosis, interstitial cystitis, and schizophrenia. It is a commonly used solvent for hydrophobic pharmaceutical agents, exhibiting effective hydroxyl radical scavenging ability. Commercially it is produced by oxidation of dimethylsulfide (DMS) with dinitrogen tetroxide. It is a component of a wide variety of foodstuffs and beverages.[1][2]

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA0526 in the slot below. This is an example certificate only and may not be the lot that you receive.

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This Item
RTC000103D20500001211006
description

Pharmaceutical Secondary Standard; Certified Reference Material

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

European Pharmacopoeia (EP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

-

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

CofA

current certificate can be downloaded

CofA

current certificate can be downloaded

CofA

-

CofA

-


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup



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Certificates of Analysis (COA)

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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. what is the water content in this DMSO product?

    1 answer
    1. The water content for this product is a lot-specific parameter that is determined by Karl Fischer Titration. For the most accurate information, kindly review the results on the lot-specific CofA.

      Please see the link below to access the Certificate for a specific lot:
      https://www.sigmaaldrich.com/search

      Helpful?

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