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425044

Sodium hypochlorite solution

reagent grade, available chlorine 10-15 %

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Linear Formula:

NaClO

CAS Number:

7681-52-9

Molecular Weight:

74.44

MDL number:

MFCD00011120

PubChem Substance ID:

329756232

NACRES:

NA.21

grade

reagent grade

Quality Level

200

vapor pressure

23.3 hPa ( 20 °C)

form

liquid

composition

available chlorine, 10-15%

reaction suitability

reagent type: oxidant

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

concentration

10-15% (chlorine by Na₂S₂O₃, titration)

bp

111 °C

density

1.206 g/mL at 25 °C

greener alternative category

Aligned

storage temp.

2-8°C

SMILES string

[Na+].[O-]Cl

InChI

1S/ClO.Na/c1-2;/q-1;+1

InChI key

SUKJFIGYRHOWBL-UHFFFAOYSA-N

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Related Categories

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Caustic Alkalis & Bases

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Downstream Process & Formulation Chemicals

Oxidation Reagents

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1 of 4

This Item	13440	1.05614	239305
Sigma-Aldrich 425044 Sodium hypochlorite solution	Sigma-Aldrich 13440 Sodium hypochlorite solution	Supelco 1.05614 Sodium hypochlorite solution	Sigma-Aldrich 239305 Sodium hypochlorite solution
form liquid	form -	form liquid	form liquid
density 1.206 g/mL at 25 °C	density -	density 1.22-1.25 g/cm³ at 20 °C	density 1.097 g/mL at 25 °C
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
Quality Level 200	Quality Level -	Quality Level 200	Quality Level -
vapor pressure 23.3 hPa ( 20 °C)	vapor pressure -	vapor pressure 20 hPa ( 20 °C)	vapor pressure 17.5 mmHg ( 20 °C)

General description

Efficacy of 2.5% sodium hypochlorite (NaOCl) solution as endodontic irrigant has been tested. It was reported as comparatively more efficient antimicrobial agent than 0.2% chlorhexidine gluconate solution. It has been proposed as tissue solvent. It has bactericidal properties. Effect of time and storage conditions on tissue-dissolving capacity of various concentrations of NaOCl have been evaluated. NaOCl is commonly used for the removal of bloom-forming or biofouling organisms. It has been proposed as algicidal agent.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is considered as an environmentally benign oxidant and has been enhanced for "Safer Solvents and Auxiliaries". Click here for more information.

Application

Sodium hypochlorite is an oxidant used with catalytic TEMPO for oxidation of alcohols. It is generally used in the synthesis of sodium 3,3′-bis(sulfonato)-4,4′-bis(acetamido)azobenzene.

Towards greener solvents for the bleach oxidation of alcohols catalysed by stable N-oxy radicals

Pictograms

GHS05,GHS09

Signal Word

Danger

Hazard Statements

H290 - H314 - H410

Precautionary Statements

P234 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Supplementary Hazards

EUH031

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.

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Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes. Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis under hypochlorite stress. In

Heat Shock Protein 70 and 90 Genes in the Harmful Dinoflagellate Cochlodinium polykrikoides: Genomic Structures and Transcriptional Responses to Environmental Stresses.

Ruoyu Guo et al.

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The marine dinoflagellate Cochlodinium polykrikoides is responsible for harmful algal blooms in aquatic environments and has spread into the world's oceans. As a microeukaryote, it seems to have distinct genomic characteristics, like gene structure and regulation. In the present study

Evaluation of epidemiological cut-off values indicates that biocide resistant subpopulations are uncommon in natural isolates of clinically-relevant microorganisms.

Ian Morrissey et al.

PloS one, 9(1), e86669-e86669 (2014-01-28)

To date there are no clear criteria to determine whether a microbe is susceptible to biocides or not. As a starting point for distinguishing between wild-type and resistant organisms, we set out to determine the minimal inhibitory concentration (MIC) and

TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway.

Eun Jo Du et al.

PLoS genetics, 12(1), e1005773-e1005773 (2016-01-05)

Pathogen expulsion from the gut is an important defense strategy against infection, but little is known about how interaction between the intestinal microbiome and host immunity modulates defecation. In Drosophila melanogaster, dual oxidase (Duox) kills pathogenic microbes by generating the

Effects of the algicides CuSO₄ and NaOCl on various physiological parameters in the harmful dinoflagellate Cochlodinium polykrikoides.

Ebenezer V, et al.

Journal of Applied Phycology, 26(6), 2357-2365 (2014)

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