Sodium carbonate

ReagentPlus®, ≥99.5%

Calcined soda, Carbonic acid disodium salt, Soda ash
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

product line





powder (granular)


12 (25 °C, 106 g/L)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)


851 °C (lit.)

SMILES string




InChI key


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500 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

Biochem/physiol Actions

Buffer component, may be used for the removal of peripheral membrane proteins.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC


Exclamation mark

Signal Word


Hazard Statements


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Nicola Palomero-Gallagher et al.
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Anterior cingulate cortex (ACC) is involved in emotion, mood, and autonomic regulation. Although a subgenual part of ACC (sACC) may be vulnerable in depression and area 25 is cytologically unique, there are no assessments that contrast this region with pregenual...
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Microalgae hold great potential as a feedstock for biofuels or bulk protein or treatment of wastewater or flue gas. Realising these applications will require the development of a cost-efficient harvesting technology. Here, we explore the potential of flocculation induced by...
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During the intraerythrocytic development of Plasmodium falciparum, the malaria parasite remodels the host cell cytosol by inducing membranous structures termed Maurer's clefts and inserting parasite proteins into the red blood cell cytoskeleton and plasma membrane. Pf332 is the largest known...
I Irwansyah et al.
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Antimicrobial hydrogels are prepared based on the co-assembly of commercial Fmoc-phenylalanine and Fmoc-leucine, which act as the hydrogelator and antimicrobial building block, respectively. This co-assembled antimicrobial hydrogel is demonstrated to exhibit selective bactericidal activity for gram-positive bacteria while being biocompatible...
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Cell metabolism, 29(6), 1243-1257 (2019-03-05)
Diffuse large B cell lymphoma (DLBCL) is a heterogeneous disease treated with anti-CD20-based immuno-chemotherapy (R-CHOP). We identified that low levels of GAPDH predict a poor response to R-CHOP treatment. Importantly, we demonstrated that GAPDHlow lymphomas use OxPhos metabolism and rely...
Proteases break peptide bonds. In the lab, it is often necessary to measure and/or compare the activity of proteases. Sigma's non-specific protease activity assay may be used as a standardized procedure to determine the activity of proteases, which is what we do during our quality control procedures.
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