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A2380

2-Aminopurine nitrate salt

≥99%

Synonym(s):

2-AP nitrate salt

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100 MG

$147.05

250 MG

$348.00

500 MG

$606.00

1 G

$1,010.00

$147.05

List Price$173.00Save 15%

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About This Item

Empirical Formula (Hill Notation):
C5H5N5 · HNO3
CAS Number:
51-16-1
Molecular Weight:
198.14
NACRES:
NA.51
PubChem Substance ID:
24890480
UNSPSC Code:
41106305
MDL number:
MFCD00038989

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Product Name

2-Aminopurine nitrate salt, ≥99%

InChI

1S/C5H5N5.HNO3/c6-5-7-1-3-4(10-5)9-2-8-3;2-1(3)4/h1-2H,(H3,6,7,8,9,10);(H,2,3,4)

SMILES string

O[N+]([O-])=O.Nc1ncc2[nH]cnc2n1

InChI key

PGDNOZBGABWZLD-UHFFFAOYSA-N

biological source

synthetic

assay

≥99%

form

powder

solubility

water: 50 mg/mL, clear, faintly to light yellow

Quality Level

100

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This Item
A3509N6125930954
2-Aminopurine nitrate salt ≥99%

Sigma-Aldrich

A2380

2-Aminopurine nitrate salt

2-Aminopurine ≥99%

Sigma-Aldrich

A3509

2-Aminopurine

Naphthol AS-TR phosphate disodium salt ≥99% (HPLC), Bulk package

Sigma-Aldrich

N6125

Naphthol AS-TR phosphate disodium salt

Aluminum nitrate nonahydrate 99.99% (trace metals basis)

Sigma-Aldrich

930954

Aluminum nitrate nonahydrate

biological source

synthetic

biological source

synthetic

biological source

-

biological source

-

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

100

form

powder

form

powder

form

powder

form

powder

assay

≥99%

assay

≥99%

assay

≥99% (HPLC)

assay

99.99% (trace metals basis)

solubility

water: 50 mg/mL, clear, faintly to light yellow

solubility

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

acetone: soluble, alcohols: soluble, water: soluble (highly soluble)

Application

2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV7707
MKCM7885
MKBR2184V
040M1902V
040M1902

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Yasumi Endoh et al.
Journal of immunology (Baltimore, Md. : 1950), 182(4), 2258-2268 (2009-02-10)
The S100 calcium-binding proteins S100A8 and S100A9 are elevated systemically in patients with viral infections. The S100A8-S100A9 complex facilitated viral replication in human CD4(+) T lymphocytes latently infected with HIV-1- and S100A8-induced HIV-1 transcriptional activity. Mechanisms inducing the S100 genes
Renata M S Pereira et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(2), 617-626 (2009-10-09)
The evolution of Leishmania infection depends on the balance between microbicidal and suppressor macrophage functions. Double-stranded RNA (dsRNA)-activated protein kinase R (PKR), a classic antiviral protein, is able to regulate a number of signaling pathways and macrophage functions. We investigated
Junpei Teramachi et al.
Experimental cell research, 316(19), 3254-3262 (2010-08-24)
Double-stranded RNA-dependent protein kinase (PKR) plays a critical role in antiviral defence of the host cells. PKR is also involved in cell cycle progression, cell proliferation, cell differentiation, tumorigenesis, and apoptosis. We previously reported that PKR is required for differentiation
Michael E Lindquist et al.
Virology, 413(1), 103-110 (2011-03-08)
We performed experiments to determine the effect of PKR activation on respiratory syncytial virus (RSV) replication. We first determined that RSV infection activates PKR which induces the phosphorylation of eIF2α, resulting in the formation of host stress granules. We used
Chen-Hsuan Wang et al.
Brain research bulletin, 79(3-4), 169-176 (2009-05-12)
Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Results showed that early induction (at 6h of
View All Related Papers

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