H8502

Dopamine hydrochloride

• Synonym(s): 2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, 3,4-Dihydroxyphenethylamine hydrochloride, 3-Hydroxytyramine hydrochloride, 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride
• Linear Formula: (HO)₂C₆H₃CH₂CH₂NH₂·HCl
• CAS Number: 62-31-7
• Molecular Weight: 189.64
• Beilstein: 3656720
• EC Number: 200-527-8
• MDL number: MFCD00012898
• PubChem Substance ID: 24277897
• NACRES: NA.77

Properties

• form: powder
• Quality Level: 200
• color: light tan
• mp: 248-250 °C (lit.)
• solubility: alcohol: 20 mg/mL; H₂O: soluble
• storage temp.: 2-8°C
• SMILES string: Cl[H].NCCc1ccc(O)c(O)c1
• InChI: 1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
• InChI key: CTENFNNZBMHDDG-UHFFFAOYSA-N
• Gene Information: human ... ADRB1(153)

Description

General description

Dopamine (DA) works as neurotransmitter in the central nervous system. It is a catecholamine made from the amino acid L-tyrosine. It also works as a hormone in vesicles of the adrenal medulla, thereby controlling heart beat rate and blood pressure. Absence of DA-containing neurons is associated with parkinson′s disease.

Application

• Dopamine hydrochloride has been used to study dopamine-mediated transient modulation of the physiological responses in whiteleg shrimp, Litopenaeus vannamei.
• It has been used to study dopamine-mediated changes in immunity susceptibility to Lactococcus garvieae in the freshwater giant prawn, Macrobrachium rosenbergii.
• It has been used to study the molecular link between dopamine-induced oxidative stress and mHtt (mutant Huntingtin) toxicity in relation to the activation of the autophagy pathway in an ‘in vitro′ model of parkinsonian Huntington′s Disease.

Packaging

1, 5, 10, 25, 100 g in poly bottle

Features and Benefits

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Caution

Light sensitive

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves