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O8010

Okadaic acid ammonium salt

From plant (Prorocentrum concavum), ≥90% (HPLC), type 1 and type 2A protein phosphatases inhibitor, solid

Synonym(s):

OA

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About This Item

Empirical Formula (Hill Notation):
C44H68O13 · NH3
CAS Number:
155716-06-6
Molecular Weight:
822.03
UNSPSC Code:
12352106
PubChem Substance ID:
24898053
NACRES:
NA.77
MDL number:
MFCD00153856

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Product Name

Okadaic acid ammonium salt from Prorocentrum concavum, ≥90% (HPLC), solid

SMILES string

[H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O

InChI key

ZBOMSHVRJSJGNR-JBNKPAQWSA-N

InChI

1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1

biological source

plant (Prorocentrum concavum)

assay

≥90% (HPLC)

form

solid

color

white

solubility

H2O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

Quality Level

200

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This Item
O7760O7885459616
Okadaic acid ammonium salt from Prorocentrum concavum ≥90% (HPLC), solid

Sigma-Aldrich

O8010

Okadaic acid ammonium salt from Prorocentrum concavum

Okadaic acid sodium salt from Prorocentrum concavum ≥90% (HPLC), film

Sigma-Aldrich

O7760

Okadaic acid sodium salt from Prorocentrum concavum

Okadaic acid potassium salt from Prorocentrum concavum ≥90% (HPLC), powder

Sigma-Aldrich

O7885

Okadaic acid potassium salt from Prorocentrum concavum

Okadaic Acid, Ammonium Salt Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.

Sigma-Aldrich

459616

Okadaic Acid, Ammonium Salt

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥98% (TLC)

form

solid

form

film

form

powder

form

solid

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 0.1 mg/mL, ethanol: soluble, DMSO: soluble

solubility

0.1% acetic acid in CH3CN: H2O (1:1): 250 μg/mL, clear, colorless

solubility

H2O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble

solubility

water: 1 mg/mL, DMSO: 20 mg/mL, ethanol: 20 mg/mL

color

white

color

translucent

color

white

color

white

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
SLCN4651
SLCF6121
SLCD0695
SLCC9868
SLBZ9425

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