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T8657

Sigma-Aldrich

Trichloroacetic acid

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

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Synonym(s):
TCA
Linear Formula:
Cl3CCOOH
CAS Number:
Molecular Weight:
163.39
Beilstein:
970119
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NB.22

vapor density

<1 (vs air)

Quality Level

vapor pressure

1 mmHg ( 51 °C)

Assay

≥99%

form

powder or flakes (or crystals)

technique(s)

electrophoresis: suitable

turbidity

≤3 NTU (1 g/ml)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

water: 1 g/mL, clear, colorless

density

1.62 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%
nitrate (NO3-): ≤0.002%
phosphate (PO43-): ≤5 ppm
sulfate (SO42-): ≤0.02%

cation traces

Fe: ≤0.0005%
heavy metals (as Pb): ≤0.002%

suitability

suitable for fixing solution (for IEF and PAGE gels)

application(s)

cell analysis

storage temp.

2-8°C

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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1 of 4

This Item
91228T6399T4885
Trichloroacetic acid suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), &#8805;99%

Sigma-Aldrich

T8657

Trichloroacetic acid

-
Trichloroacetic acid BioUltra, &#8805;99.5% (T)

Sigma-Aldrich

91228

Trichloroacetic acid

Premium Grade
Trichloroacetic acid ACS reagent, &#8805;99.0%

Sigma-Aldrich

T6399

Trichloroacetic acid

-
Trichloroacetic acid &#8805;99.0% (titration)

Sigma-Aldrich

T4885

Trichloroacetic acid

-
vapor pressure

1 mmHg ( 51 °C)

vapor pressure

1 mmHg ( 51 °C)

vapor pressure

1 mmHg ( 51 °C)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99%

assay

≥99.5% (T)

assay

≥99.0%

assay

≥99.0% (titration)

form

powder or flakes (or crystals)

form

crystals, flakes

form

-

form

-

refractive index

n20/D 1.62 (lit.)

refractive index

n20/D 1.62 (lit.)

refractive index

n20/D 1.62 (lit.)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

bp

196 °C (lit.)

bp

196 °C (lit.)

bp

196 °C (lit.)

General description

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Application

Trichloroacetic acid has been used:
  • for hydrolysis of DNA isolated from the cell
  • for precipitation of glutathione isolated from seminal plasma
  • as a fixative in microscopy

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

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HEPES

SAFC

PHG0001

HEPES

Cryotherapy compared with trichloroacetic acid in treating genital warts.
Godley MJ
Sexually Transmitted Infections, 63(6), 390-392 (1987)
Teratogenic activity of trichloroacetic acid in the rat
Smith MK, et al.
Teratology, 40(5), 445-451 (1989)
Atmospheric pressure pulsed plasma induces cell death in photosynthetic organs via intracellularly generated ROS
Seol Y, et al.
Scientific reports, 7(1), 589-589 (2017)
Quantitation of DNA fragmentation with diphenylamine
Boraschi D and Maurizi G
Apoptosis-a laboratory manual of experimental methods, 153-161 (1998)
Determination of total protein in spinal fluid with sulphosalicylic acid and trichloroacetic acid
Meulemans O
Clinica Chimica Acta; International Journal of Clinical Chemistry, 5(5), 757-761 (1960)

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