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  • Cross-reactivities of various phenethylamine-type designer drugs to immunoassays for amphetamines, with special attention to the evaluation of the one-step urine drug test Instant-View™, and the Emit® assays for use in drug enforcement.

Cross-reactivities of various phenethylamine-type designer drugs to immunoassays for amphetamines, with special attention to the evaluation of the one-step urine drug test Instant-View™, and the Emit® assays for use in drug enforcement.

Forensic science international (2011-12-14)
Keiko Nakanishi, Akihiro Miki, Kei Zaitsu, Hiroe Kamata, Noriaki Shima, Tooru Kamata, Munehiro Katagi, Michiaki Tatsuno, Hitoshi Tsuchihashi, Koichi Suzuki
ABSTRACT

Cross-reactivities of 76 kinds of phenethylamine-type designer drugs and related compounds to the urine drug tests Instant-View ™ (IV) (the Methamphetamine (MA) test, the Amphetamine 300 test, and the MDMA test) have been investigated. An on-site urine test kit consisting of these three IV tests has been evaluated for the on-site screening of MA users, and the kit has been found to have satisfactory specificity for drug enforcement purposes by separately detecting both MA and its metabolite amphetamine. The cross-reactivity profiles of Emit(®) II Plus Amphetamines Assay, Emit(®) II Plus Ecstasy assay, and Emit(®) d.a.u.(®) Amphetamine Class assay have also been investigated and discussed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Phenethylamine, 99%
Sigma-Aldrich
2-Phenylethylamine hydrochloride, ≥98%
Sigma-Aldrich
Phenethylamine, ≥99%
Supelco
2-Phenethylamine, analytical standard
Sigma-Aldrich
Phenethylamine, purified by redistillation, ≥99.5%