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Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.

Scientific reports (2017-07-01)
Marie Hennebelle, Zhichao Zhang, Adam H Metherel, Alex P Kitson, Yurika Otoki, Christine E Richardson, Jun Yang, Kin Sing Stephen Lee, Bruce D Hammock, Liang Zhang, Richard P Bazinet, Ameer Y Taha
ABSTRACT

Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain. Here, we show that oxidized LA-derived metabolites accumulate in several rat brain regions during CO

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meso-Tetraphenylporphyrin, BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

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