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Merck

CYP2C9

cytochrome P450, family 2, subfamily C, polypeptide 9

Sinónimos:
CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
Especie:
ID UniProtKB:
ID del gen:
  • Human(1559) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti Cytochrome P450 2C9 Antibody, clone 23GB5885, Rabbit Monoclonal, clone 23GB5885, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
western blot
Anti-CYP2C9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Thiabendazole, ≥99%, powder,
Especie
human
3,3′-Methylene-bis(4-hydroxycoumarin), ,
Especie
human
Sulfaphenazole, ≥98%,
Especie
human
Benzbromarone, analytical standard,
Especie
human
Phenylbutazone, ,
Especie
human

Proteins

Número de producto
Descripción
Especie
CypExpress 2C9 Cytochrome P450 human, ,
Especie
human
Cytochrome P450 2C9*2 (R144C), human, recombinant, expressed in E. coli,
Especie
human
Cytochrome P450 2C9*3 (I359L), human, recombinant, expressed in E. coli,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human CYP2C9,
Especie
human

Small Molecule - Substrate

Número de producto
Descripción
Especie
Tolbutamide, analytical standard,
Especie
human, mouse