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259527

1,2-Dimethoxyethane

anhydrous, 99.5%, inhibitor-free

1 of 2 reviewers took part in a promotion

Synonym(s):

DME, mono-Glyme, Dimethylglycol, Ethylene glycol dimethyl ether, Monoglyme

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Size/SKUAvailabilityPrice
100 mL
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$124.00
1 L
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$236.00
2 L
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$379.00
6 x 1 L
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$1,190.00
12 x 100 mL
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$1,250.00
10 L
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$1,330.00

About This Item

Linear Formula:
CH3OCH2CH2OCH3
CAS Number:
Molecular Weight:
90.12
UNSPSC Code:
12352112
NACRES:
NA.21
EC Number:
203-794-9
Beilstein/REAXYS Number:
1209237
MDL number:
PubChem Substance ID:
Assay:
99.5%
Grade:
anhydrous
Bp:
85 °C (lit.)
Vapor pressure:
48 mmHg ( 20 °C)

$124.00


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grade

anhydrous

Quality Segment

vapor density

3.1 (20 °C, vs air)

vapor pressure

48 mmHg ( 20 °C)

assay

99.5%

form

liquid

autoignition temp.

396 °F

expl. lim.

10.4 %

impurities

<0.003% water, <0.005% water (100 mL pkg)

evapn. residue

<0.0005%

refractive index

n20/D 1.379 (lit.)

pH

7

bp

85 °C (lit.)

mp

−58 °C (lit.)

density

0.867 g/mL at 25 °C (lit.)

SMILES string

COCCOC

InChI

1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3

InChI key

XTHFKEDIFFGKHM-UHFFFAOYSA-N

General description

Our anhydrous solvents deliver exceptionally low water content, making them the ideal choice for moisture-sensitive laboratory applications. Packaged in the exclusive Sure/Seal™ septum bottle system, they are reliably protected against moisture ingress from first use to last drop. The innovative Sure/Seal™ closure combines an advanced plug-style liner with an airtight elastomer and crimp cap design to ensure consistent product integrity. Three unique liner materials provide optimal chemical compatibility across a broad range of solvents. Sure/Seal™ packaging is proven to maintain anhydrous conditions even after repeated punctures. With more than 70 products across all major solvent families, available in pack sizes from 100 mL to 2 L, the portfolio meets virtually every laboratory need. By choosing ready-to-use anhydrous solvents in Sure/Seal™ packaging, researchers eliminate the need for time-consuming and hazardous in-house solvent drying and distillation - saving time, reducing risk, and improving reproducibility.

Application

Anhydrous solvents in Sure/Seal™ packaging are essential wherever water contamination would compromise experimental results. They are widely used in moisture-sensitive applications such as organic synthesis - including Grignard reactions, organometallic chemistry, and catalysis - as well as in peptide, oligonucleotide, and pharmaceutical synthesis.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

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Show Differences

1 of 1

This Item
E27408724051601463
description

anhydrous, 99.5%, inhibitor-free

description

ReagentPlus®, ≥99%, inhibitor-free

description

analytical standard

description

United States Pharmacopeia (USP) Reference Standard

assay

99.5%

assay

≥99%

assay

≥99.7% (GC)

assay

-

grade

anhydrous

grade

-

grade

analytical standard

grade

pharmaceutical primary standard

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

form

liquid

form

liquid

form

-

form

-

vapor density

3.1 (20 °C, vs air)

vapor density

3.1 (20 °C, vs air)

vapor density

3.1 (20 °C, vs air)

vapor density

-

pH

7

pH

7

pH

-

pH

-


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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

supp_hazards

Storage Class

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

41.0 °F - closed cup

Flash Point (°C)

5 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Questions

1–3 of 3 Questions  
  1. How is the anhydrous DME sealed? Is it under argon or nitrogen? I plan to transfer it into a vacuum/argon glovebox and would like to confirm the appropriate way to open and store it to avoid contamination.

    1 answer
    1. The material is packed under nitrogen gas. Storage details are found in section 7 of the product's SDS. It is shipped in the Sure/Seal packaging format, details of which can be found here: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/685/583/al_techbull_al134.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

1 of 2 reviewers took part in a promotion
1–2 of 2 Reviews  

Active Filters

  1. Pasadena
    • Review 1
    • Votes 3
    5 out of 5 stars.

    Wow!

    Pure by NMR! No water! This is the real deal guys...

    Helpful?

  2. Chapel Hill, NC
    • Reviews 3
    • Votes 2
    5 out of 5 stars.

    Excellent for cross couplings

    My cross couplings always work just a little better when ran in DME. Sigma products never fail to deliver when it comes to C-C bond formation.

    Helpful?