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Fibroblast Growth Factor from bovine pituitary

Name: Fibroblast Growth Factor from bovine pituitary
Brand: SIGMA
Price: 396 USD
Availability: InStock

lyophilized, suitable for cell culture

Synonym(s):

FGF

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Pack Size	SKU	Availability	Price
10 μg		Estimated to ship onJune 02, 2026fromMILWAUKEE	$396.00

About This Item

CAS Number:

62031-54-3

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD00166724

Biological source:

bovine pituitary glands

Form:

lyophilized powder

Mol wt:

16.4 kDa

Impurities:

endotoxin, tested

$396.00

Estimated to ship onJune 02, 2026Details

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Properties

Product Name

Fibroblast Growth Factor from bovine pituitary, suitable for cell culture

biological source

bovine pituitary glands

Quality Level

200

form

lyophilized powder

potency

1-100 ng/mL

mol wt

16.4 kDa

packaging

pkg of 10 and 5X10 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

storage temp.

−20°C

Description

General description

Fibroblast growth factors (FGF) are glycoproteins concealed in the extracellular matrix and cell surface. There are around 22 different types of FGFs known. These factors weigh in the range of 17 to 34kDa and they possess a conserved sequence of 120 amino acids.

Application

A natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.

Fibroblast Growth Factor from bovine pituitary has been used in in vitro testicular cell culture. It has also been used as a component of myogenic culture medium.

Biochem/physiol Actions

Fibroblast growth factors (FGF) actively participate in cellular responses including embryogenesis and organogenesis. It specifically controls cell proliferation, differentiation and migration. FGF is known to regulate nervous system functions, tissue repair mechanism and wound healing. It also controls angiogenesis of tumor cells. Abnormal FGF mediated signaling induces tumor angiogenesis, by stimulating cancer cell proliferation and survival. FGFs carries out its function by mediating through four receptor tyrosine kinases : FGF-receptors FGFR1, FGFR2, FGFR3 and FGFR4.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.1 mg/ml BSA.

Preparation Note

Purified glands by a modification of the method of Gospodarowicz.

Analysis Note

Although the major mitogenic component of this product is FGF2, the activity per unit weight of protein is less than that of purified FGF2.

The biological activity is measured using a 3-day MTT assay.

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This Item	F5392	F3685	F5542
Sigma-Aldrich F3133 Fibroblast Growth Factor from bovine pituitary	Sigma-Aldrich F5392 Fibroblast Growth Factor-Basic from bovine pituitary	Sigma-Aldrich F3685 Fibroblast Growth Factor-Basic	Sigma-Aldrich F5542 Fibroblast Growth Factor-Acidic human
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable
biological source bovine pituitary glands	biological source bovine pituitary glands	biological source human	biological source human
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
storage condition avoid repeated freeze/thaw cycles	storage condition avoid repeated freeze/thaw cycles	storage condition avoid repeated freeze/thaw cycles	storage condition avoid repeated freeze/thaw cycles
impurities endotoxin, tested	impurities <0.5 EU/vial	impurities -	impurities ≤1.0 EU/mg (LAL test)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

Fibroblast Growth Factor Family (FGF)

Fibroblast growth factors in cell culture and various growth factors for your research

Global Trade Item Number

SKU	GTIN
F3133-10UG	04061833613528
F3133-5X10UG	04061833613535

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