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I9135

Anti-Human IgG (Fc specific) antibody produced in rabbit

whole antiserum

Synonym(s):

Human Antiserum, Rabbit Anti Human IgG - Anti-Human IgG (Fc specific) antibody produced in rabbit, Rabbit Anti Human Igg, Rabbit Antiserum

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Size/SKUAvailabilityPrice
2 mL
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$166.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), QPA
Citations:
9

$166.00


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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:100,000, quantitative precipitin assay: 1.5 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

IgG contains four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, that are associated by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.

Application

Anti-Human IgG (Fc specific) antibody produced in rabbit was used in immunoblotting and immunocytochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Biochem/physiol Actions

IgG activates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a pivotal role in antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. It might be linked to allergy and has the longest serum half life.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Preparation Note

treated to remove lipoproteins

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I8885I6260SAB4200682
description

whole antiserum

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whole antiserum

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clone GG-7, ascites fluid

description

clone GG-7, purified from hybridoma cell culture

technique(s)

quantitative precipitin assay: 1.5 mg/mL, indirect ELISA: 1:100,000

technique(s)

quantitative precipitin assay: 4.0-7.0 mg/mL, indirect ELISA: 1:50,000

technique(s)

indirect ELISA: 1:40,000

technique(s)

immunofluorescence: suitable, indirect ELISA: 0.25-0.5 μg/mL using 5μg/mL human IgG for coating., ELISA: suitable

biological source

rabbit

biological source

goat

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

antibody form

whole antiserum

antibody form

whole antiserum

antibody form

ascites fluid

antibody form

purified immunoglobulin

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

clone

polyclonal

clone

polyclonal

clone

GG-7, monoclonal

clone

GG-7, monoclonal


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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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