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| Size/SKU | Availability | Price |
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100 μL | Check Cart for Availability | $552.00 |
About This Item
biological source
mouse
Quality Segment
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
HP-6001, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
indirect ELISA: 0.5 μg/mL using 1 μg/mL Human IgG1 myeloma protein for coating.
isotype
IgG2b
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
The amount of the different IgG subclasses present in the bloodstream varies with age. For example, IgG1 and IgG3 reach normal adult levels by 5-7 years of age while IgG2 and IgG4 levels raise more slowly, reaching adult levels at about 10 years of age. Serum IgG subclass deficiencies have been recorded for different patient groups. For example, a disproportionate elevation of IgG1 has been found in the cerebral spinal fluid of patients with multiple sclerosis.Examination of the distribution pattern of IgG subclasses in different types of diseases may provide insight into the immunological processes involved and may assist in the diagnosis of various disorders.
Monoclonal Anti-Human IgG1 (Fc specific) specifically recognizes Fc region of Human IgG1. The antibody shows no cross-reactivity with human IgG2, IgG3 and IgG4. This clone has been established as a useful human IgG1 specificity standard by the WHO/IUIS.
Immunogen
Application
Physical form
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description clone HP-6001, purified from hybridoma cell culture | description clone GG-7, purified from hybridoma cell culture | description clone HP-6001, ascites fluid | description clone GG-7, purified from hybridoma cell culture |
| species reactivity human | species reactivity human | species reactivity - | species reactivity human |
| clone HP-6001, monoclonal | clone GG-7, monoclonal | clone HP-6001, monoclonal | clone GG-7, monoclonal |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| antibody form purified from hybridoma cell culture | antibody form purified immunoglobulin | antibody form ascites fluid | antibody form purified from hybridoma cell culture |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| isotype IgG2b | isotype IgG1 | isotype IgG2b | isotype IgG1 |
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Storage Class
12 - Non Combustible Liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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