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T2501

L-Thyroxine sodium salt pentahydrate

synthetic (organic), ≥98% (HPLC), Thyroid hormone, powder

Synonym(s):

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

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Size/SKUAvailabilityPrice
1 g

Available to ship TODAYfromMILWAUKEE

$196.00
5 g

Available to ship TODAYfromMILWAUKEE

$786.00

About This Item

Linear Formula:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
CAS Number:
Molecular Weight:
888.93
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-221-4
MDL number:
Beilstein/REAXYS Number:
5721845
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥98% (HPLC)

$196.00


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Product Name

L-Thyroxine sodium salt pentahydrate, ≥98% (HPLC), powder

biological source

synthetic (organic)

Quality Segment

sterility

non-sterile

assay

≥98% (HPLC)

form

powder

mp

207-210 (dec.) (lit.)

solubility

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

Gene Information

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Preparation Note

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

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biological source

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biological source

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biological source

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biological source

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assay

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assay

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assay

≥98% (HPLC)

assay

≥98% (HPLC)

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Quality Level

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Quality Level

200

form

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form

powder

form

powder

form

powder

shipped in

ambient

shipped in

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shipped in

ambient

shipped in

ambient

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

room temp


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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