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Vascular Endothelial Growth Factor 164 from rat

Name: Vascular Endothelial Growth Factor 164 from rat
Brand: SIGMA
Price: 626.45 USD
Availability: InStock

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

VEGF 164, VEGF-164, VEGF₁₆₄, Vasculotropin

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Size/SKU	Availability	Price
10 μg	Available to ship TODAYfromMILWAUKEE	$737.00 $626.45

About This Item

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD01636149

Biological source:

rat

Recombinant:

expressed in NSO cells

Assay:

>95% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

dimer 50 kDa by SDS-PAGE, monomer 25 kDa by SDS-PAGE

Impurities:

endotoxin, tested

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Properties

Product Name

Vascular Endothelial Growth Factor 164 from rat, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

biological source

rat

Quality Segment

200

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

1.08 ng/mL ED₅₀

mol wt

dimer 50 kDa by SDS-PAGE, monomer 25 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

P16612

storage temp.

−20°C

Gene Information

rat ... Vegfa(83785)

Description

Application

Vascular Endothelial Growth Factor 164 (VEGF 164) from rat was used for cardiomyocytes culture and Ca²⁺ transients′ measurement. It was used as a medium M-199 supplement utilized in in vitro incubation for examining the capability of CTS to limit the impact of biologically relevant molecules, in particular epidermal growth factor (EGF), basic fibroblast growth factor (FGF2), and vascular endothelial growth factor A (VEGFA) in rat epididymis segment 1 and 2.

Biochem/physiol Actions

Vascular Endothelial Growth Factor 164 also referred to as VEGF 164 or Vasculotropin is a growth factor that induces endothelial cell growth, vasculogenesis and angiogenesis. VEGF 164 can enhance collagen and fibronectin expression in mesangial cells which in turn stimulates TGF-β1-induced extracellular matrix. It also plays a pivotal role in progressive glomerular fibrosis.

Mitogen for endothelial cells, enhances vascular permeability, activates, and chemoattracts monocytes and is a procoagulant.

Physical form

Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 0.5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to stimulate ³H-thymidine incorporation in human umbilical vein endothelial cells.

Other Notes

164 amino acid variant of rat VEGF.

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This Item	P5739	V4512	V7259
Sigma-Aldrich V3638 Vascular Endothelial Growth Factor 164 from rat	Sigma-Aldrich P5739 Placenta Growth Factor-2 from mouse	Sigma-Aldrich V4512 Vascular Endothelial Growth Factor from mouse	Sigma-Aldrich V7259 Vascular Endothelial Growth Factor human
description >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder	description lyophilized powder, recombinant, expressed in baculovirus infected Sf21 cells, suitable for cell culture	description VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture	description VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture
assay >95% (SDS-PAGE)	assay >97% (SDS-PAGE)	assay ≥98% (SDS-PAGE)	assay ≥98% (SDS-PAGE)
recombinant expressed in NSO cells	recombinant expressed in baculovirus infected Sf21 cells	recombinant expressed in E. coli	recombinant expressed in E. coli
biological source rat	biological source mouse	biological source mouse	biological source human
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
form lyophilized powder	form lyophilized powder	form powder	form powder
UniProt accession no. P16612	UniProt accession no. P49764	UniProt accession no. Q00731	UniProt accession no. P15692

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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