really cool indicator! definitely would recommend to friend!
105945
Phenolphthalein
ACS reagent
Phenolphthalein
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Sinônimo(s):
3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
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Sobre este item
Fórmula empírica (Notação de Hill):
C20H14O4
Número CAS:
Peso molecular:
318.32
Número do índice de cores:
764
Beilstein:
284423
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de substância PubChem:
NACRES:
NA.47
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ACS reagent
Nível de qualidade
Formulário
powder
técnica(s)
titration: suitable
visual transition interval
8.0-10, colorless to red
pf
261-263 °C (lit.)
solubilidade
acetone: soluble
densidade
1.27 g/cm3 at 32 °C
λmax
374 nm (2nd)
552 nm
aplicação(ões)
diagnostic assay manufacturing
hematology
histology
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4
InChI
1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H
chave InChI
KJFMBFZCATUALV-UHFFFAOYSA-N
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Este Item | 04479 | 1.07233 |
|---|---|---|
| technique(s) titration: suitable | technique(s) - | technique(s) - |
| grade ACS reagent | grade certified reference material, TraceCERT® | grade ACS reagent |
| application(s) diagnostic assay manufacturing | application(s) - | application(s) - |
| form powder | form - | form solid |
| solubility acetone: soluble | solubility acetone: soluble | solubility - |
| storage temp. room temp | storage temp. - | storage temp. 2-30°C |
Descrição geral
Phenolphthalein is an indicator for acid-base titration reactions.[1] It changes from colorless to violet-red between pH 8.3-9.8, it is red in extremely acidic solutions, and colorless in extremely alkaline solutions.[2]
It is present as a nonionic, lipophilic lactone in aqueous neutral solutions. It exists as a hydrophilic dianion in alkaline solutions.
It is present as a nonionic, lipophilic lactone in aqueous neutral solutions. It exists as a hydrophilic dianion in alkaline solutions.
Aplicação
Phenolphthalein has been commonly used as an indicator in the fields of biology and medicine. Its applications include:
- the development of novel technique to monitor the vacuum freeze-drying process[3]
- the determination of the depth of carbonation in concrete[4]
- the utilization of liquid marbles to sense gaseous environmental components
- the estimation of total acidity in vinegar
- the assessment of sodium hydroxide penetration into potatoes following chemical peeling
- as a model organic compound in the evaluation of the capture efficiency of various cyclodextrin constructs such as nanofiber-CD
Ações bioquímicas/fisiológicas
Phenolphthalein is colorless in acidic solutions and turns pink in basic solutions.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Carc. 1B - Muta. 2 - Repr. 2 - Skin Irrit. 2
Código de classe de armazenamento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Using phenolphthalein as a promising indicator to monitor the vacuum freeze-drying process
Liu, et al.
Materials Letters, 139 (2015)
Conn?s Biological Stains: A Handbook of Dyes, Stains and Fluorochromes for Use in Biology and Medicine (10th ed.)
RW Horobin, JW Kiernan (Eds.)
Conn?s Biological Stains (2002)
Min Guk Kim et al.
Journal of personalized medicine, 10(4) (2020-10-15)
Unbalanced dietary habits and the consumption of high protein and instant foods cause an increase in constipation. Here, we evaluated the effects of galacto-oligosaccharide (GOS) on a rat model of loperamide-induced constipation by measuring various biological markers and cecal microbiota.
Teaching New Tricks to an Old Indicator: pH-Switchable, Photoactive Microporous Polymer Networks from Phenolphthalein with Tunable CO2 Adsorption Power
Kiskan, et al.
Macromolecules (2012)
The experimental investigation of concrete carbonation depth
Cheng-Feng Chang, Jing-Wen Chen
Cement and Concrete Research, 36(9) (2006)
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