85558

Spermidine

BioUltra, for molecular biology, ≥99.5% (GC)

• Synonym(s): 1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane
• Linear Formula: NH₂(CH₂)₃NH(CH₂)₄NH₂
• CAS Number: 124-20-9
• Molecular Weight: 145.25
• Beilstein: 1698591
• Número EC: 204-689-0
• Número MDL: MFCD00008229
• ID de substância PubChem: 57653053
• NACRES: NA.26

Properties

• grau: for molecular biology
• Nível de qualidade: 200
• linha de produto: BioUltra
• teor: ≥99.5% (GC)
• Impurezas: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• índice de refração: n20/D 1.479 (lit.)
• pH: 12.0-13.5 (25 °C, 1 M in H₂O)
• solubilidade: H₂O: 1 M at 20 °C, clear, colorless
• densidade: 0.925 g/mL at 25 °C (lit.)
• traços de ânion: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• traços de cátion: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorção UV: λ: 260 nm A_max: 0.1; λ: 280 nm A_max: 0.05
• SMILES string: NCCCCNCCCN
• InChI: 1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
• InChI key: ATHGHQPFGPMSJY-UHFFFAOYSA-N
• Gene Information: rat ... Ppm1a(24666)

Description

Descrição geral

Spermidine is a polyamine and a trivalent organic cation.

Aplicação

Spermidine has been used:

• as a component of chromosome isolation buffer
• as a component of transcription buffer
• as a component of homogenization buffer

Embalagem

1, 5, 25 g

Ações bioquímicas/fisiológicas

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Spermidine modulates various cellular activities like cellular growth and development, stability of DNA and apoptosis.

Atenção

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Nota de análise

liquid or solid

Outras notas

In first strand cDNA synthesis; Effect on endonuclease inhibition by agarose contaminants

Safety Information

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H314
• Declarações de precaução: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Classificações de perigo: Eye Dam. 1 - Skin Corr. 1B
• Código de classe de armazenamento: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• Ponto de fulgor (ºF): 233.6 °F - closed cup
• Ponto de fulgor (ºC): 112 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter