L-Asparaginsäure

Name: <SC>L</SC>-Asparaginsäure
Brand: SIAL

certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(e):

(S)-2-Amino-bernsteinsäure, (S)-2-Aminobutandisäure

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Lineare Formel:

HO₂CCH₂CH(NH₂)CO₂H

CAS-Nummer:

56-84-8

Molekulargewicht:

133.10

Beilstein:

1723530

EG-Nummer:

200-291-6

MDL-Nummer:

MFCD00002616

UNSPSC-Code:

41116107

PubChem Substanz-ID:

329757712

NACRES:

NA.24

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Qualität

certified reference material
TraceCERT^®

Qualitätsniveau

300

Produktlinie

TraceCERT^®

chemische Klasse(n) des Analyten

amino acids, peptides, proteins

Hersteller/Markenname

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

>300 °C (dec.) (lit.)

Anwendung(en)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Format

neat

SMILES String

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChIKey

CKLJMWTZIZZHCS-REOHCLBHSA-N

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Dieser Artikel	PHR1104	A7219	A5474
Supelco 51572 L-Asparaginsäure	Supelco PHR1104 L-Asparaginsäure	Sigma-Aldrich A7219 L-Asparaginsäure	SAFC A5474 L-Asparaginsäure
application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care pharmaceutical (small molecule)	application(s) -	application(s) pharmaceutical (small molecule)
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
format neat	format neat	format -	format -
Quality Level 300	Quality Level 300	Quality Level 300	Quality Level 400
grade certified reference material, TraceCERT^®	grade certified reference material, pharmaceutical secondary standard	grade -	grade -
manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	manufacturer/tradename -	manufacturer/tradename -	manufacturer/tradename -

Allgemeine Beschreibung

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out the entire portfolio of our amino acids certified reference materials (CRM)

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Haupt-Neurotransmitter für schnelle synaptische Erregung.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Rechtliche Hinweise

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Unsynchronised subunit motion in single trimeric sodium-coupled aspartate transporters.

Guus B Erkens et al.

Nature, 502(7469), 119-123 (2013-10-05)

Excitatory amino acid transporters (EAATs) are secondary transport proteins that mediate the uptake of glutamate and other amino acids. EAATs fulfil an important role in neuronal signal transmission by clearing the excitatory neurotransmitters from the synaptic cleft after depolarization of

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase.

Ann-Louise Johansson et al.

Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8912-8917 (2013-05-16)

Proton transfer across biological membranes underpins central processes in biological systems, such as energy conservation and transport of ions and molecules. In the membrane proteins involved in these processes, proton transfer takes place through specific pathways connecting the two sides

Direct metal recognition by guanine nucleotide-exchange factor in the initial step of the exchange reaction.

Tamami Uejima et al.

Acta crystallographica. Section D, Biological crystallography, 69(Pt 3), 345-351 (2013-03-23)

Rab small GTPases regulate vesicle transport in eukaryotes by interacting with various effectors. Guanine nucleotide-exchange factor (GEF) catalyzes the transition from inactive GDP-bound Rab to active GTP-bound Rab. The existence of several GDP-bound intermediates containing the Arabidopsis thaliana Rab5 homologue

Kinetics of isomerization and inversion of aspartate 58 of αA-crystallin peptide mimics under physiological conditions.

Kenzo Aki et al.

PloS one, 8(3), e58515-e58515 (2013-03-19)

Although proteins consist exclusively of L-amino acids, we have reported that aspartyl (Asp) 58 and Asp 151 residues of αA-crystallin of eye lenses from elderly cataract donors are highly inverted and isomerized to D-β, D-α and L-β-Asp residues through succinimide

Chasing protons: how isothermal titration calorimetry, mutagenesis, and pKa calculations trace the locus of charge in ligand binding to a tRNA-binding enzyme.

Manuel Neeb et al.

Journal of medicinal chemistry, 57(13), 5554-5565 (2014-06-24)

Drug molecules should remain uncharged while traveling through the body and crossing membranes and should only adopt charged state upon protein binding, particularly if charge-assisted interactions can be established in deeply buried binding pockets. Such strategy requires careful pKa design

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