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Merck

GPX1

glutathione peroxidase 1

Sinonimi:
GPXD, GSHPX1
Specie:
ID UniProtKB:
ID gene:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo monoclonale ANTI-FLAG® M2-perossidasi (HRP), clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
all
Applicazione
ELISA
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
alligator, human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
ANTI-GPX1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-GPX1 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-Gpx1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, mouse, rat
Applicazione
ELISA
western blot

Proteins

Numero di prodotto
Descrizione
Specie
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human GPX1,
Specie
human