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Merck

O8010

Okadaic acid ammonium salt

From plant (Prorocentrum concavum), ≥90% (HPLC), type 1 and type 2A protein phosphatases inhibitor, solid

別名:

OA

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10 μG

￥17,290

25 μG

￥35,165

50 μG

￥60,905

￥17,290

単価￥24,700割引30%
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この商品について

実験式（ヒル表記法）:
C44H68O13 · NH3
CAS番号:
155716-06-6
分子量:
822.03
UNSPSC Code:
12352106
PubChem Substance ID:
24898053
NACRES:
NA.77
MDL number:
MFCD00153856

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製品名

オカダ酸 アンモニウム塩 渦鞭毛藻Prorocentrum concavum由来, ≥90% (HPLC), solid

SMILES string

[H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O

InChI key

ZBOMSHVRJSJGNR-JBNKPAQWSA-N

InChI

1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1

biological source

plant (Prorocentrum concavum)

assay

≥90% (HPLC)

form

solid

color

white

solubility

H2O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

Quality Level

200

関連するカテゴリー

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1 of 4

当該品目
O7760O7885459616
オカダ酸 アンモニウム塩 渦鞭毛藻Prorocentrum concavum由来 ≥90% (HPLC), solid

Sigma-Aldrich

O8010

オカダ酸 アンモニウム塩 渦鞭毛藻Prorocentrum concavum由来

オカダ酸 ナトリウム塩 渦鞭毛藻Prorocentrum concavum由来 ≥90% (HPLC), film

Sigma-Aldrich

O7760

オカダ酸 ナトリウム塩 渦鞭毛藻Prorocentrum concavum由来

オカダ酸 カリウム塩 渦鞭毛藻Prorocentrum concavum由来 ≥90% (HPLC), powder

Sigma-Aldrich

O7885

オカダ酸 カリウム塩 渦鞭毛藻Prorocentrum concavum由来

Okadaic Acid, Ammonium Salt Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.

Sigma-Aldrich

459616

Okadaic Acid, Ammonium Salt

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥98% (TLC)

form

solid

form

film

form

powder

form

solid

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 0.1 mg/mL, ethanol: soluble, DMSO: soluble

solubility

0.1% acetic acid in CH3CN: H2O (1:1): 250 μg/mL, clear, colorless

solubility

H2O: 0.1 mg/mL, DMSO: soluble, ethanol: soluble

solubility

water: 1 mg/mL, DMSO: 20 mg/mL, ethanol: 20 mg/mL

color

white

color

translucent

color

white

color

white

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
SLCN4651
SLCF6121
SLCD0695
SLCC9868
SLBZ9425

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文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

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Connective tissue research, 61(6), 554-567 (2019-07-12)
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Immune-checkpoint blockade has revolutionized cancer treatment, but some cancers, such as acute myeloid leukemia (AML), do not respond or develop resistance. A potential mode of resistance is immune evasion of T cell immunity involving aberrant major histocompatibility complex class I (MHC-I)
Dong-Keon Kim et al.
Cancers, 12(9) (2020-09-17)
Octamer-binding transcription factor 4 (Oct4) plays an important role in maintaining pluripotency in embryonic stem cells and is closely related to the malignancies of various cancers. Although posttranslational modifications of Oct4 have been widely studied, most of these have not
Yun-Ling He et al.
Cell death & disease, 13(11), 966-966 (2022-11-18)
Mitophagy is an important metabolic mechanism that modulates mitochondrial quality and quantity by selectively removing damaged or unwanted mitochondria. BNIP3 (BCL2/adenovirus e1B 19 kDa protein interacting protein 3), a mitochondrial outer membrane protein, is a mitophagy receptor that mediates mitophagy under
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