- Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones.
Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones.
FEBS letters (2014-12-03)
Pierre-Alexandre Lallement, Edgar Meux, José M Gualberto, Stéphane Dumarcay, Frédérique Favier, Claude Didierjean, Frederick Saul, Ahmed Haouz, Mélanie Morel-Rouhier, Eric Gelhaye, Nicolas Rouhier, Arnaud Hecker
PMID25455804
ABSTRACT
Glutathionyl-hydroquinone reductases (GHRs) catalyze the deglutathionylation of quinones via a catalytic cysteine. The two GHR genes in the Populus trichocarpa genome, Pt-GHR1 and Pt-GHR2, are primarily expressed in reproductive organs. Both proteins are localized in plastids. More specifically, Pt-GHR2 localizes in nucleoids. At the structural level, Pt-GHR1 adopts a typical GHR fold, with a dimerization interface comparable to that of the bacterial and fungal GHR counterparts. Pt-GHR1 catalyzes the deglutathionylation of both reduced and oxidized glutathionylated quinones, but the enzyme is more catalytically efficient with the reduced forms.
MATERIALS
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Brand
Product Description
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