Superoxide is the critical driver of DOPAL autoxidation, lysyl adduct formation, and crosslinking of alpha-synuclein
Werner-Allen JW, et al.
Biochemical and Biophysical Research Communications, 487(2), 281-286 (2017)
Detection of Intracellular Reduced (Catalytically Active) SHP-1 and Analyses of Catalytically Inactive SHP-1 after Oxidation by Pervanadate or H2O2
Choi S and Love PE
Bio-protocol, 8(1) (2018)
Bach1 induces endothelial cell apoptosis and cell-cycle arrest through ROS generation
Wang X, et al.
Oxidative Medicine and Cellular Longevity, 2016(1) (2016)
Shoichi Iriguchi et al.
Blood, 125(2), 370-382 (2014-10-29)
Although overexpression of T-bet, a master transcription factor in type-1 helper T lymphocytes, has been reported in several hematologic and immune diseases, its role in their pathogenesis is not fully understood. In the present study, we used transgenic model mice...
James R Van Brocklyn et al.
Cancer research, 74(19), 5364-5370 (2014-08-12)
Glioblastoma remains a devastating disease for which novel therapies are urgently needed. Here, we report that the Aurora-A kinase inhibitor alisertib exhibits potent efficacy against glioblastoma neurosphere tumor stem-like cells in vitro and in vivo. Many glioblastoma neurosphere cells treated...