TP63
tumor protein p63
同義詞:
AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
物種:
Human TP63 (8626), Rat Tp63 (246334), Zebrafish tp63 (260407), chicken TP63 (374269), dog TP63 (488125), domestic cat TP63 (101095124), domestic guinea pig Tp63 (100732143), Horse TP63 (100059752), sheep TP63 (101108874), sheep TP63 (100048992) ...更多
UniProtKB ID:
基因 ID:
- Human(8626) Summary: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]
- Rat(246334) tumor protein p63
- Zebrafish(260407) tumor protein p63
- chicken(374269) tumor protein p63
- dog(488125) tumor protein p63
- domestic cat(101095124) tumor protein p63
- domestic guinea pig(100732143) tumor protein p63
- Horse(100059752) tumor protein p63
- sheep(101108874) tumor protein p63
- sheep(100048992) tumor protein p63
- naked mole-rat(101710600) tumor protein p63
- cow(615335) tumor protein p63
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
產品編號
描述
物種活性
應用
Anti-p40 Antibody, from rabbit, purified by affinity chromatography,
物種活性
human, mouse
應用
immunohistochemistry
western blot
western blot
Anti-P40 Antibody, clone 11F12.1, clone 11F12.1, from mouse,
物種活性
human
應用
immunohistochemistry
western blot
western blot
Anti-P40 Antibody, clone 11F12.1, Alexa Fluor™ 488, clone 11F12.1, from mouse, ALEXA FLUOR™ 488,
物種活性
human, mouse
應用
immunocytochemistry
Anti-tp63 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
zebrafish
應用
immunohistochemistry
western blot
western blot
Anti-P40 Antibody, clone 11F12.1, Alexa Fluor™ 647, clone 11F12.1, from mouse, ALEXA FLUOR™ 647,
物種活性
human, mouse
應用
immunocytochemistry
Proteins
產品編號
描述
物種
p63, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human