391333

HEPES sodium salt

ULTROL^® Grade, ≥99% dry basis (titration), zwitterionic N-substituted aminosulfonic acid buffer

• Synonym(s): HEPES, Sodium Salt, ULTROL^® Grade, N-2-Hydroxyethylpiperazine-Nʹ-2-ethanesulfonic Acid, Na
• Empirical Formula (Hill Notation): C₈H₁₇N₂O₄S · Na
• CAS Number: 75277-39-3
• Molecular Weight: 260.29
• MDL number: MFCD00036463
• UNSPSC Code: 12161704
• NACRES: NA.25

Properties

• Product Name: HEPES sodium salt, ULTROL^® Grade, ≥99% dry basis (titration), zwitterionic N-substituted aminosulfonic acid buffer
• SMILES string: [Na+].[S](=O)(=O)([O-])CCN1CCN(CC1)CCO
• InChI: 1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1
• InChI key: RDZTWEVXRGYCFV-UHFFFAOYSA-M
• assay: ≥99% dry basis (titration)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• pKa (20 °C): 7.6
• solubility: water: 1.0 M
• anion traces: chloride (Cl^-): <0.01%; sulfate (SO₄^2-): <0.05%
• cation traces: heavy metals: <1 ppm
• shipped in: ambient
• storage temp.: 15-25°C
• Quality Level: 100

Description

Application

• 3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism.: This study explores the antibacterial mechanisms of a chitosan derivative, which could be related to the buffering capabilities of HEPES in maintaining the stability and exposure of functional groups necessary for antibacterial activity (Yan et al., 2016).

Disclaimer

Toxicity: Standard Handling (A)

General description

A zwitterionic N-substituted aminosulfonic acid buffer(Absorbance: <0.10 at 260 nm, 1.0 mM, H₂O). Active in the pH range of 6.0 to 8.5. Has a pK_a of 7.6 at 20°C.

Absorbance (1.0 mM, H₂O, 260 nm):<0.10.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable