AB1921

Anti-Integrin alpha 5 (ITGA5/CD49E) Antibody

Name: Anti-Integrin alpha 5 (ITGA5/CD49E) Antibody
Brand: MM
Price: 519 USD

CHEMICON^®, rabbit polyclonal

Synonym(s):

CD49e

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100 μL

$519.00

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Key Documents

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Product Name

Anti-Integrin α5 Antibody, serum, Chemicon^®

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_002205.2

UniProt accession no.

P08648

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGA5(3678)

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Show Differences

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This Item	MAB2575	MABT820	AB1936
Sigma-Aldrich AB1921 Anti-Integrin α5 Antibody	Sigma-Aldrich MAB2575 Anti-Integrin α5β1 Antibody, clone BMC5	Sigma-Aldrich MABT820 Anti-Integrin alpha 5 (CD49e) Antibody, clone mAb16	Sigma-Aldrich AB1936 Anti-Integrin α2 Antibody
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form serum	antibody form ascites fluid	antibody form purified antibody	antibody form serum
biological source rabbit	biological source rat	biological source rat	biological source rabbit
shipped in wet ice	shipped in dry ice	shipped in ambient	shipped in wet ice
species reactivity mouse	species reactivity mouse	species reactivity human	species reactivity chicken, rat, hamster, mouse, human
technique(s) ELISA: suitable, western blot: suitable, immunohistochemistry: suitable	technique(s) flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable	technique(s) immunocytochemistry: suitable, immunoprecipitation (IP): suitable, inhibition assay: suitable	technique(s) ELISA: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, radioimmunoassay: suitable, western blot: suitable

Immunogen

Recombinant fragment of mouse alpha5 integrin (Holers et al. 1989) corresponding to amino acid residues 655-880 of the human protein (Argraves 1987). This region of the molecule is extracellular and is included in the heavy chain (120 kDa).

Application

Detect Integrin α5 using this Anti-Integrin α5 Antibody validated for use in ELISA, WB, IH.

ELISA.

Western blotting: (The antigen should be separated in SDS-PAGE under reducing conditions

and does not react with non-reduced sample.): 1:5,000.

Immunohistochemistry/Immunofluorescence: 1:1,000.

Optimal working dilutions must be determined by the end user.

Research Category
Cell Structure

Research Sub Category
Integrins

Biochem/physiol Actions

Specific for alpha5 integrin as determined by Western blotting.

Physical form

Whole rabbit serum. Liquid, with 0.02% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pricing

ZRB1122

Anti-Integrin α-5 Antibody, clone 5E18 ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells

Storage Class

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension.

Coyer, SR; Singh, A; Dumbauld, DW; Calderwood, DA; Craig, SW; Delamarche, E; Garcia, AJ

Journal of Cell Science null

CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes.

Nishida, T; Kawaki, H; Baxter, RM; Deyoung, RA; Takigawa, M; Lyons, KM

Journal of Cell Communication and Signaling null

Opposing effects of collagen I and vitronectin on fibronectin fibril structure and function.

Gildner, CD; Roy, DC; Farrar, CS; Hocking, DC

Matrix Biology null

Akt and RhoA inhibition promotes anoikis of aggregated B16F10 melanoma cells.

Oumou Goundiam et al.

Cell biology international, 36(3), 311-319 (2011-11-11)

In the highly metastatic B16F10 melanoma cell line, activation of the signalling molecules that promote cell proliferation and survival on conventional adhesive culture dishes may also be responsible for the growth and resistance to anoikis of aggregates on a non-adhesive

Recombinant fibronectin matrix mimetics specify integrin adhesion and extracellular matrix assembly.

Roy, DC; Hocking, DC

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