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K2012

Sigma-Aldrich

Ketoprofen

meets USP testing specifications

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Synonym(s):
2-(3-Benzoylphenyl)propionic acid
Empirical Formula (Hill Notation):
C16H14O3
CAS Number:
Molecular Weight:
254.28
EC Number:
MDL number:
PubChem Substance ID:

agency

USP/NF
meets USP testing specifications

Quality Level

form

solid

application(s)

pharmaceutical (small molecule)

SMILES string

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

Gene Information

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This Item
PHR1375K1751I7905
Ketoprofen meets USP testing specifications

K2012

Ketoprofen

Ketoprofen Pharmaceutical Secondary Standard; Certified Reference Material

PHR1375

Ketoprofen

Ketoprofen ≥98% (TLC)

K1751

Ketoprofen

Ibuprofen meets USP testing specifications

I7905

Ibuprofen

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

200

form

solid

form

-

form

powder

form

solid

agency

USP/NF

agency

traceable to BP 668, traceable to Ph. Eur. K2000000, traceable to USP 1356632

agency

-

agency

USP/NF, meets USP testing specifications

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

Biochem/physiol Actions

Non-steroidal anti-inflammatory compound that is selective for COX-1.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Elisabeth Christiansen et al.
Journal of medicinal chemistry, 54(19), 6691-6703 (2011-08-23)
The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already
Ikram Ullah Khan et al.
International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)
Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free
Nathalie C Newby et al.
Journal of dairy science, 96(3), 1511-1520 (2013-01-22)
Surgical correction of left displaced abomasum (LDA) is common in lactating dairy cattle. Despite the growing acceptance that abdominal surgery is painful, few cows are administered analgesia following LDA surgery. The objective of this research was to examine the effect
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
Marcello Allegretti et al.
Journal of medicinal chemistry, 48(13), 4312-4331 (2005-06-25)
The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs by binding the seven-transmembrane (7-TM) G-protein-coupled receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2

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