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S8263

Sigma-Aldrich

Sodium hydroxide solution

5.0 M

Linear Formula:
NaOH
CAS Number:
Molecular Weight:
40.00
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

for molecular biology

vapor pressure

3 mmHg ( 37 °C)

form

liquid

concentration

5.0 M

pH

14

density

1.327 g/cm3 at 25 °C

storage temp.

room temp

SMILES string

[OH-].[Na+]

InChI

1S/Na.H2O/h;1H2/q+1;/p-1

InChI key

HEMHJVSKTPXQMS-UHFFFAOYSA-M

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Application

Sodium hydroxide solution can be used:
  • As a base in the reduction of oximes, imines, and hydrazones using Raney nickel.
  • In the preparation of trans-1,2-cyclohexanediaminetetraacetic acid standard solution applicable in the synthesis of the ferric chelate complex.
  • In the synthesis of radiolabeled quinolinyl analogs for α-synuclein binding assay studies.

Packaging

150 mL in poly bottle

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Convenient method for reduction of CN double bonds in oximes, imines, and hydrazones using sodium borohydride-Raney Ni system
Yang Y, et al.
Synthetic Communications, 42, 2540-2554 (2012)
Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation
Yue X, et al.
Bioorganic & medicinal chemistry letters, 28, 1011-1019 (2018)
Solubility of dimethyldisulfide (DMDS) in aqueous solutions of Fe (III) complexes of trans-1, 2-cyclohexanediaminetetraacetic acid (CDTA) using the static headspace method
Iliuta MC and Larachi F
Fluid Phase Equilibria, 233, 184-189 (2005)
Richard J Travers et al.
Blood, 124(22), 3183-3190 (2014-09-10)
Polyphosphate (polyP) is secreted by activated platelets and has been shown to contribute to thrombosis, suggesting that it could be a novel antithrombotic target. Previously reported polyP inhibitors based on polycationic substances, such as polyethylenimine, polyamidoamine dendrimers, and polymyxin B
Horacio Cardenas et al.
Epigenetics, 9(11), 1461-1472 (2014-12-04)
A key step in the process of metastasis is the epithelial-to-mesenchymal transition (EMT). We hypothesized that epigenetic mechanisms play a key role in EMT and to test this hypothesis we analyzed global and gene-specific changes in DNA methylation during TGF-β-induced

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