All Photos(3)

E6758

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

All Photos(3)

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

Linear Formula:

(HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂

CAS Number:

60-00-4

Molecular Weight:

292.24

Beilstein:

1716295

EC Number:

200-449-4

MDL number:

MFCD00003541

eCl@ss:

39030907

PubChem Substance ID:

24894634

NACRES:

NA.25

grade

anhydrous

Quality Level

200

product line

BioReagent

assay

≥98.5%

form

crystalline

technique(s)

cell culture | mammalian: suitable

mp

250 °C (dec.) (lit.)

solubility

3 M NaOH: 100 mg/mL

density

1.46 g/cm³ at 20 °C

cation traces

C: 40.7-41.5%
N: 9.3-9.8%

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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Related Categories

Chelating & Reducing Agents

Application

Ethylenediaminetetraacetic acid has been used:

as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
as a medium component in the hepatic stellate cell (HSCs) culture
as a component of homogenization buffer for protein extraction from eye tissues
for stopping benzonase reaction in lysis buffer

Packaging

100, 500 g in poly bottle

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)