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OLIGO

Custom DNA Oligos

Design and Order Custom Oligos

Synonym(s):
High-throughput DNA, Oligonucleotides, DNA, Oligos in plates, ISO 13485 Oligos, Oligonucleotide, Next−generation sequencing oligos, Oligos, Next−generation sequencing adapters, Locked Nucleic Acid oligos, Modified oligos, NGS−grade oligos, DNA primer, Custom DNA Oligos, NGS adapters

Important Update

Beginning May 8, 2022, BHQ™ (Black Hole Quencher™) 1 and 2 will no longer be available as a modification to Custom DNA Oligos and Custom qPCR Probes. The replacements will be BXQ™ (Block All Quencher™) 1 and 2. Information about the BXQ dark quenchers will be added from time-to-time to key oligo landing pages up until the date of change. As these key landing pages are updated, this message will be updated to provide links to the new information. If you have any questions, please contact your local company representative.

Alternatively, to learn more about BXQ, please visit the manufacturer’s website: BXQ | AAT Bioquest.


Standard DNA Oligos

  • Scale: 0.025, 0.05, 0.2, 1.0, 10, and 15 μmol
  • Purification: Desalt, Cartridge, HPLC, and PAGE
  • Sequence Length: Up to 120 bases
  • Modifications: Over 200 available, including dyes (fluorescent and non-fluorescent)
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry or in solution – tubes, plates and mixed plates (forward and reverse primers)
  • WellRED Oligos: Available
  • qPCR Probes: Available
  • Learn more about Standard DNA Synthesis
  • NOW AVAILABLE: Same Day Custom Oligos, order today and receive tomorrow

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Plates


Easy Oligo

  • Amount: 3 OD
  • Concentration: 100 µM
  • Purification: Desalt
  • Sequence Length: 15 - 30 bases
  • Modifications: Not available
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied in solution
  • Ships within 24 hours of order receipt
  • Learn more

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Pure & Simple Primers

  • Amount: 3 OD
  • Purification: Cartridge
  • Sequence Length: 12 - 35 bases
  • Modifications: Not available
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry
  • Ships within 24 hours of order receipt
  • Learn more

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iScale Oligos™ (mg & g quantity)

  • Larger quantities for in vivo, high throughput and commercial projects
  • Quantity: 10, 25, 50, 100, 250, and 500 mg (Inquire for larger quantities)
  • Purification: Desalt, RP-HPLC, & In vivo
  • Sequence Length: 10 - 50 bases (Inquire for longer lengths)
  • Modifications: Biotin, Phosphate, Amino-Modifier C12, & others
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry
  • Services: Salt Exchange, Endotoxin Testing, & Filtration
  • Learn more

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Next-Gen Sequencing Oligos

  • Custom universal and index (barcode) adapter oligos for major sequencing platforms
  • Suitable purity (percent full-length sequence) to maintain sequence read integrity
  • Low levels of cross-contamination to facilitate proper sequence assembly
  • Learn more

Commercial Oligos

  • Custom DNA Primers, qPCR Probes, and Next-Gen Sequencing Oligos for Life Science Research Tools, Molecular Diagnostics (ISO 13485 manufacturing available), and Laboratory Developed Tests
  • Component or complete kit manufacturing, including custom formulations, packaging, and private labeling
  • Learn more

Locked Nucleic Acid

  • Available with Custom DNA Oligos
  • Increased thermal stability and hybridization specificity
  • Easier and more specific designs for problematic target sequences
  • Learn more

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Fuqiang Chen et al.
Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)...
T N Wiegner et al.
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of...
Leonel Armas-López et al.
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be...
Eun Jung Thak et al.
Journal of microbiology (Seoul, Korea), 56(1), 11-23 (2018-01-05)
Protein glycosylation, the most universal and diverse post-translational modification, can affect protein secretion, stability, and immunogenicity. The structures of glycans attached to proteins are quite diverse among different organisms and even within yeast species. In yeast, protein glycosylation plays key...
Hyong Woo Choi et al.
PloS one, 10(11), e0143447-e0143447 (2015-11-26)
The plant hormone salicylic acid (SA) controls several physiological processes and is a key regulator of multiple levels of plant immunity. To decipher the mechanisms through which SA's multiple physiological effects are mediated, particularly in immunity, two high-throughput screens were...

Articles

Custom DNA Oligos Modifications

We offer over 200 modifications for both DNA and RNA oligonucleotides and probes.

Protocols

Custom Molecular Reference Standards and Controls

When developing an MDx assay, it is vital to use reference standards and controls. Standards are used for developing the assay, whereas controls are used to assess final working assay quality. Our custom long DNA and RNA are platform independent and ideal for use with common technologies, such as PCR and NGS.

Related Content

Oligonucleotide FAQ (Frequently Asked Questions)

Oligonucleotides are short DNA or RNA molecules that are used in genetic testing, research, and forensics. Custom oligos are synthesized using phosphoramidite chemistry. See some of the most frequently asked questions regarding our custom oligo synthesis service.

Custom DNA Oligos Modifications

We offer over 200 custom DNA oligos modification for both DNA, RNA oligonucleotides and sequencing to probes for gene.

OligoArchitect™ Consultative

For more complex and demanding applications, utilize our consultative service to ensure the success of your assay.

Oligonucleotide Label Licenses

Label licenses for our oligonucleotide products, including Black Hole Quencher®, BlackBerry® Quencher, and Locked Nucleic Acid (LNA®).

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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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