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P8865

SAFC

L-Proline

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Synonym(s):
(S)-Pyrrolidine-2-carboxylic acid
Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
Molecular Weight:
115.13
Beilstein:
80810
EC Number:
MDL number:
NACRES:
NA.26

biological source

non-animal source

Quality Level

Assay

≥98.5%

form

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, residual solvents, tested

mp

228 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

application(s)

pharmaceutical (small molecule)

foreign activity

cytotoxicity, tested

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

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This Item
C5360A5474G5792
L-Proline

SAFC

P8865

L-Proline

L-Cysteine

SAFC

C5360

L-Cysteine

L-Aspartic acid

SAFC

A5474

L-Aspartic acid

L-Glutamine

SAFC

G5792

L-Glutamine

form

crystalline powder

form

crystalline powder

form

crystalline powder

form

powder

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, residual solvents, tested

impurities

endotoxin, heavy metals, trace metals, tested

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

impurities

endotoxin, heavy metals, residual solvents, tested

mp

228 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

mp

185 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

solubility

H2O: 25 mg/mL

solubility

1 M HCl: 50 mg/mL

solubility

H2O: 25 mg/mL

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Proline is a non-essential amino acid. Peptides bond to Proline, making it a useful building block for proteins. It can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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705578-5MG-PW

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