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U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

Synonym(s):

UTP

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25 μMOL

$107.10

$107.10

List Price$126.00Save 15%

Estimated to ship onDecember 04, 2025fromSAINT LOUIS

About This Item

MDL number:
MFCD00044310
UNSPSC Code:
41106305
PubChem Substance ID:
24900622
NACRES:
NA.52

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biological source

yeast (Candida Utilis)

assay

≥95 (HPLC)

form

liquid

concentration

100 mM in H2O (adjusted to pH 7 with Trizma®
base)

color

colorless

foreign activity

DNase and RNase, none detected

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

InChI key

MMJGIWFJVDOPJF-LLWADOMFSA-K

Gene Information

human ... P2RY2(5029)
rat ... P2ry2(29597)

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1 of 4

This Item
G3776D0184T9656
Uridine 5′-triphosphate trisodium salt solution HPLC purified, aqueous solution for RNA polymerase transcription

Sigma-Aldrich

U1006

Uridine 5′-triphosphate trisodium salt solution

Guanosine 5′-triphosphate sodium salt solution HPLC purified, aqueous solution for RNA polymerase transcription

Sigma-Aldrich

G3776

Guanosine 5′-triphosphate sodium salt solution

2′-Deoxyuridine 5′-triphosphate sodium salt solution 100 mM in H2O

Sigma-Aldrich

D0184

2′-Deoxyuridine 5′-triphosphate sodium salt solution

Thymidine 5′-triphosphate sodium salt solution 100 mM in H2O

Sigma-Aldrich

T9656

Thymidine 5′-triphosphate sodium salt solution

biological source

yeast (Candida Utilis)

biological source

Porcine brain, bacterial (Corynebacterium), yeast

biological source

-

biological source

synthetic (organic)

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

200

assay

≥95 (HPLC)

assay

≥95% (HPLC)

assay

≥99%

assay

≥99%

form

liquid

form

liquid

form

liquid

form

liquid

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Application

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca2+ levels in rat primary tracheal epithelial cells.[1] It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).[2]

Biochem/physiol Actions

P2Y receptor agonist
UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA.[3] It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis.[4] UTP is involved in the production of ATP, which is essential for metabolic reactions.[3]
Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000494158
0000494158
0000375452
0000375452
SLCN0184

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Uridine metabolism and its role in glucose, lipid, and amino acid homeostasis
Zhang Y, et al.
BioMed Research International, 2020 (2020)
Aloa Lamarca et al.
PloS one, 9(6), e98998-e98998 (2014-06-07)
In response to peripheral nerve injury, Schwann cells adopt a migratory phenotype and modify the extracellular matrix to make it permissive for cell migration and axonal re-growth. Uridine 5'-triphosphate (UTP) and other nucleotides are released during nerve injury and activate
Biochemistry of uridine in plasma
Yamamoto T, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 412(19-20), 1712-1724 (2011)
Ann-Sofie Jemth et al.
Nucleic acids research, 46(20), 10888-10904 (2018-10-12)
Nucleotides in the free pool are more susceptible to nonenzymatic methylation than those protected in the DNA double helix. Methylated nucleotides like O6-methyl-dGTP can be mutagenic and toxic if incorporated into DNA. Removal of methylated nucleotides from the nucleotide pool
Anne Hahn et al.
Physiological reports, 5(12) (2017-06-24)
Transport of water and electrolytes in airway epithelia involves chloride-selective ion channels, which are controlled either by cytosolic Ca2+ or by cAMP The contributions of the two pathways to chloride transport differ among vertebrate species. Because rats are becoming more

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