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67028 Sigma-Aldrich

Methylglyoxal solution

technical, ~40% in H2O

Synonym: Acetylformaldehyde, Pyruvaldehyde, Pyruvic aldehyde

  • CAS Number 78-98-8

  • Linear Formula CH3COCHO

  • Molecular Weight 72.06

  •  Beilstein/REAXYS Number 906750

  •  MDL number MFCD00006960

  •  PubChem Substance ID 329760261

  •  NACRES NA.22

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Properties

Related Categories Aldehydes, Building Blocks, C1 to C6, Carbonyl Compounds, Cell Biology,
Quality Level   200
grade   technical
concentration   ~40% in H2O
density   1.19 g/mL at 20 °C
storage temp.   2-8°C
SMILES string   [H]C(=O)C(C)=O
InChI   1S/C3H4O2/c1-3(5)2-4/h2H,1H3
InChI key   AIJULSRZWUXGPQ-UHFFFAOYSA-N

Description

General description

Methylglyoxal is a toxic endogenous by-product of glycolysis. It is a reactive dicarbonyl compound that promotes non-enzymatic glycation of proteins to yield irreversible advanced glycated end products, leading to the cross-linking or degradation of proteins.

Application

Methylglyoxal solution is used in cytotoxic studies.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
RIDADR 
UN 3265 8 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

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