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D1260 Sigma-Aldrich

Decamethonium bromide

crystalline

Synonym: Decamethylene bis(trimethylammonium bromide), Decane-1,10-bis(trimethylammonium bromide)

  • CAS Number 541-22-0

  • Linear Formula (CH3)3N(Br)(CH2)10N(Br)(CH3)3

  • Molecular Weight 418.29

  •  Beilstein/REAXYS Number 3728288

  •  EC Number 208-772-2

  •  MDL number MFCD00011779

  •  PubChem Substance ID 24277833

  •  NACRES NA.77

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Properties

Related Categories Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
form   crystalline
color   off-white
mp   263-267 °C (lit.)
originator   GlaxoSmithKline
SMILES string   [Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
InChI   1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
InChI key   HLXQFVXURMXRPU-UHFFFAOYSA-L
Gene Information   human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

Description

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.

Packaging

5, 10, 25 g in glass bottle

Biochem/physiol Actions

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.

Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
BP5950000
Protocols & Articles
Peer-Reviewed Papers
15

References

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