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D1260 Sigma-Aldrich

Decamethonium bromide

crystalline

Synonym: Decamethylene bis(trimethylammonium bromide), Decane-1,10-bis(trimethylammonium bromide)

  • CAS Number 541-22-0

  • Linear Formula (CH3)3N(Br)(CH2)10N(Br)(CH3)3

  • Molecular Weight 418.29

  •  Beilstein Registry Number 3728288

  •  EC Number 208-772-2

  •  MDL number MFCD00011779

  •  PubChem Substance ID 24277833

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Properties

Related Categories Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   HLXQFVXURMXRPU-UHFFFAOYSA-L
form   crystalline
color   off-white
mp   263-267 °C (lit.)
originator   GlaxoSmithKline
Gene Information   human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

Description

Packaging

5, 10, 25 g in glass bottle

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.

Biochem/physiol Actions

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.

Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
BP5950000

Making Headway

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Peer-Reviewed Papers
15

References

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