D1260

Decamethonium bromide

crystalline

• Synonym(s): Decamethylene bis(trimethylammonium bromide), Decane-1,10-bis(trimethylammonium bromide)
• Linear Formula: (CH₃)₃N(Br)(CH₂)₁₀N(Br)(CH₃)₃
• CAS Number: 541-22-0
• Molecular Weight: 418.29
• Beilstein/REAXYS Number: 3728288
• EC Number: 208-772-2
• MDL number: MFCD00011779
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277833
• NACRES: NA.77

Properties

• form: crystalline
• Quality Level: 200
• color: off-white
• mp: 263-267 °C (lit.)
• originator: GlaxoSmithKline
• SMILES string: [Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
• InChI key: HLXQFVXURMXRPU-UHFFFAOYSA-L
• Gene Information: human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143), CHRND(1144), CHRNE(1145), CHRNG(1146)

Description

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.[1]

Biochem/physiol Actions

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.[2]

Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335
• pcodes: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges