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Bioactive Small Molecules

Our portfolio features over 4,000 potent, selective probes to modulate target activity for almost any pathway and all major target classes, including highly characterized chemical probes in partnership with the Structural Genomics Consortium.  

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Structural Genomics Consortium

Structural Genomics Consortium (SGC) chemical probes for target validation and numerous additional research applications and workflow needs.

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Use our bioactive small molecule explorer to find your fit-for-purpose probe. 

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bioactive small molecules (1998)

inhibitors (174)

peptides (54)

hormones (50)

agonists (25)

antibiotics (25)

neuroscience (677)

cell biology (563)

cell signaling and structure BSM (160)

neuron science BSM (100)

immunology (84)

immuno BSM and signaling proteins (41)

white (1140)

yellow (153)

off-white (127)

colorless (25)

red (18)

orange (16)
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Showing 1-20 of 2184
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Showing 1-20 of 2184
4-Hydroxytamoxifen
H6278

4-Hydroxytamoxifen

≥98% (HPLC), powder, Estrogen receptor antagonist

Dopamine hydrochloride
H8502

Dopamine hydrochloride

≥98% (TLC), powder, neurotransmitter

Cholera Toxin from <I>Vibrio cholerae</I>
C8052

Cholera Toxin

from Vibrio cholerae, ≥90% (SDS-PAGE), lyophilized powder, A-B type toxin

(Z)-4-Hydroxytamoxifen
H7904

(Z)-4-Hydroxytamoxifen

≥98% (HPLC), powder, estrogen receptor modulator

Antimycin A from <I>Streptomyces</I> sp.
A8674

Antimycin A

from Streptomyces sp., mitochondrial electron transport chain complex III inhibitor, powder

CHIR99021
SML1046

CHIR99021

≥98% (HPLC), powder, GSK-3 inhibitor

Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
C2920

Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone

≥98% (HPLC), powder, Mitophagy inducer

Y-27632
688001

Y-27632

≥95% (HPLC), liquid, Rho kinase inhibitor, Calbiochem®

Diphtheria Toxin from <I>Corynebacterium diphtheriae</I>
D0564

Diphtheria Toxin

from Corynebacterium diphtheriae, ≥98% (SDS-PAGE), lyophilized powder, protein synthesis inhibitor

Sunflower seed oil from <I>Helianthus annuus</I>
S5007

Sunflower seed oil

from Helianthus annuus, liquid, emollient

Oligomycin from <I>Streptomyces diastatochromogenes</I>
O4876

Oligomycin

from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC), powder, antibiotic

Capsaicin
M2028

Capsaicin

from Capsicum sp., ≥95% (HPLC), powder, TRPV1 agonist

Serotonin hydrochloride
H9523

Serotonin hydrochloride

≥98%, powder, neurotransmitter

DAPT
D5942

DAPT

≥98% (HPLC), solid, γ-secretase inhibitor

SB 202190
S7067

SB 202190

≥98% (HPLC), powder, p38 MAP kinase inhibitor

<I>N</I><SUB>ω</SUB>-Nitro-<SC>L</SC>-arginine methyl ester hydrochloride
N5751

Nω-Nitro-L-arginine methyl ester hydrochloride

≥97% (TLC), powder, nitric oxide production inhibitor

MG-132
474790

MG-132

≥98% (HPLC), proteasome inhibitor, solid

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
M0896

MPTP Hydrochloride

≥98% (AgNO3), powder, dopaminergic neurotoxin

A 83-01
SML0788

A 83-01

≥98% (HPLC), powder, TGF-β RI kinase inhibitor

Deferoxamine mesylate salt
D9533

Deferoxamine mesylate salt

≥92.5% (TLC), powder, iron-chelating agent

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