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MilliporeSigma

Nucleic Acid Purification

The purity, quality, and quantity of your nucleic acid samples depends on reliable nucleic acid purification reagents and kits. We offer a variety of suitable kits for your nucleic acid sample needs, including gDNA, RNA, and plasmid purification, single spin purification, nucleic acid amplification, nucleic acid gel extraction, PCR clean-up, and more. Explore our comprehensive offering to maximize the reproducibility of your results and minimize the time spent on nucleic acid purification and related workflow needs.   

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RNA Purification

RNA purification is a critical first step in many analyses due to the easy degradability of RNA. GenElute™ RNA purification kits enable purification of RNA from a variety of sources quickly and efficiently with minimal degradation, maximum purity, and high recovery and yield. GenElute™-E Single Spin RNA purification kits can be used to clean up RNA preps in a single spin for PCR and downstream applications.

Reaction Clean-Up

Cleanup of PCR reactions, restriction digests, sequencing reactions, and agarose and polyacrylamide gel extracts is essential for removing contaminants such as salts, enzymes, unincorporated dNTPs, primers, ethidium bromide, and other impurities that can interfere with downstream analysis. A selection of products for cleaning up DNA and RNA from enzymatic reactions or pre-purified samples is available for flexibility and convenience.

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gDNA Purification
gDNA Purification

High yield, high quality DNA extraction and purification kits tailored to a variety of common and challenging sample types including cell culture, mammalian tissue, blood, viruses, bacteria, plant tissue, soil, water, urine, stool, PCR reactions, and agarose gel extractions.

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Plasmid DNA Purification
Plasmid DNA Purification

Plasmid DNA purification kits offered in miniprep, midiprep, maxiprep, and gigaprep sizes for small to large scale purification of plasmid DNA for molecular cloning, transformation, and recombinant protein expression applications.

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kits (88)

master mixes (5)

plates (4)

buffers (2)

enzymes (2)

PCR reagents (1)

DNA purification (34)

PCR (24)

RNA purification (12)

DNA extraction (8)

qPCR (3)

RT-PCR (2)

Millipore (8)

Sigma-Aldrich (91)
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TRI Reagent<SUP>®</SUP>
T9424

TRI Reagent®

For processing tissues, cells cultured in monolayer or cell pellets

RNA<I>later</I><SUP>®</SUP>
R0901

RNAlater®

Stabilize and protect RNA with immediate RNase inactivation

RNaseZAP<SUP>™</SUP>
R2020

RNaseZAP

Cleaning agent for removing RNase

REDExtract-N-Amp<SUP>™</SUP> PCR ReadyMix<SUP>™</SUP>
R4775

REDExtract-N-Amp PCR ReadyMix

Ready-to-use 2X PCR Master Mix with Loading Dye

REDExtract-N-Amp<SUP>™</SUP> Tissue PCR Kit
XNAT

REDExtract-N-Amp Tissue PCR Kit

sufficient for 10 reactions, sufficient for 100 reactions, sufficient for 1000 reactions, hotstart, dNTPs included

Extract-N-Amp<SUP>™</SUP> PCR ReadyMix<SUP>™</SUP>
E3004

Extract-N-Amp PCR ReadyMix

Amplifications to support Extract-N-Amp Plant and Extract-N-Amp Tissue

Spectrum<SUP>™</SUP> Plant Total RNA Kit
STRN50

Spectrum Plant Total RNA Kit

sufficient for 50 purifications

Spectrum<SUP>™</SUP> Plant Total RNA Kit
STRN250

Spectrum Plant Total RNA Kit

sufficient for 250 purifications

GenElute<SUP>™</SUP> Bacterial Genomic DNA Kits
NA2110

GenElute Bacterial Genomic DNA Kits

sufficient for 70 purifications

RNAzol<SUP>®</SUP> RT
R4533

RNAzol® RT

For processing total and small RNA from human, animal, plant, bacterial,and viral samples

High Pure RNA Tissue Kit
12033674001

High Pure RNA Tissue Kit

sufficient for 50 isolation(s), suitable for RT-PCR, suitable for Northern blotting

GenElute<SUP>™</SUP> Plasmid Miniprep Kit
PLN70

GenElute Plasmid Miniprep Kit

sufficient for 70 purifications

High Pure PCR Product Purification Kit
HPPCRPKRO

High Pure PCR Product Purification Kit

sufficient for 250 purifications (11732676001), sufficient for 50 purifications (11732668001), suitable for DNA purification

Extract-N-Amp<SUP>™</SUP> Tissue PCR Kit
XNAT2

Extract-N-Amp Tissue PCR Kit

sufficient for 100 extractions, sufficient for 100 amplifications

RNase AWAY<SUP>®</SUP>
83931

RNase AWAY®

decontamination reagent for RNase

GenElute<SUP>™</SUP> PCR Clean-Up Kit
NA1020

GenElute PCR Clean-Up Kit

sufficient for 70 purifications

GenElute<SUP>™</SUP> Gel Extraction Kit
NA1111

GenElute Gel Extraction Kit

sufficient for 70 purifications

GenElute<SUP>™</SUP> Plasmid Miniprep Kit
PLN350

GenElute Plasmid Miniprep Kit

sufficient for 350 purifications

High Pure Plasmid Isolation Kit
HPPIKRO

High Pure Plasmid Isolation Kit

Roche, pkg of 50 purifications (11754777001), pkg of 250 purifications (11754785001)

DNA Isolation Kit for Mammalian Blood
11667327001

DNA Isolation Kit for Mammalian Blood

pkg of 1 kit sufficient for 25 purifications

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