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Bioactive Small Molecules

Our portfolio features over 4,000 potent, selective probes to modulate target activity for almost any pathway and all major target classes, including highly characterized chemical probes in partnership with the Structural Genomics Consortium.  


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Structural Genomics Consortium

Structural Genomics Consortium (SGC) chemical probes for target validation and numerous additional research applications and workflow needs.



Need help finding a bioactive small molecule?

Use our bioactive small molecule explorer to find your fit-for-purpose probe. 


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bioactive small molecules (2285)

inhibitors (170)

hormones (71)

peptides (71)

antibiotics (35)

agonists (22)

neuroscience (768)

cell biology (626)

cell signaling and structure BSM (175)

neuron science BSM (111)

immunology (103)

immuno BSM and signaling proteins (49)

white (1276)

yellow (168)

off-white (142)

colorless (28)

red (18)

orange (16)
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Showing 1-20 of 2506
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Tamoxifen
T5648

Tamoxifen

≥99% (TLC), powder, PKC inhibitor

Phorbol 12-myristate 13-acetate
P8139

Phorbol 12-myristate 13-acetate

≥99% (TLC), film or powder, PKC activator

Streptozocin
S0130

Streptozocin

≥75% α-anomer basis,≥98% (HPLC), powder, DNA alkylating agent

4-Hydroxytamoxifen
H6278

4-Hydroxytamoxifen

≥98% (HPLC), powder, Estrogen receptor antagonist

Retinoic acid
R2625

Retinoic acid

≥98% (HPLC), powder, RAR and RXR ligand

3-Isobutyl-1-methylxanthine
I5879

3-Isobutyl-1-methylxanthine

≥99% (HPLC), cAMP and cGMP phosphodiesterases inhibitor, powder

Dopamine hydrochloride
H8502

Dopamine hydrochloride

≥98% (TLC), powder, neurotransmitter

Cholera Toxin from <I>Vibrio cholerae</I>
C8052

Cholera Toxin

from Vibrio cholerae, ≥90% (SDS-PAGE), lyophilized powder, A-B type toxin

Ionomycin calcium salt from <I>Streptomyces conglobatus</I>
I0634

Ionomycin calcium salt

from Streptomyces conglobatus, ≥98% (HPLC), powder, Ca2+ ionophore

(Z)-4-Hydroxytamoxifen
H7904

(Z)-4-Hydroxytamoxifen

≥98% (HPLC), powder, estrogen receptor modulator

Choline chloride
C1879

Choline chloride

synthetic, ≥98%, Choline acetyltransferase substrate, powder or crystals

Y-27632 dihydrochloride
Y0503

Y-27632 dihydrochloride

synthetic (organic), ≥98% (HPLC), ROCK inhibitor, powder

Guanosine 5′-triphosphate sodium salt hydrate
G8877

Guanosine 5′-triphosphate sodium salt hydrate

≥95% (HPLC), RNA synthesis substrate, powder

Antimycin A from <I>Streptomyces</I> sp.
A8674

Antimycin A

from Streptomyces sp., mitochondrial electron transport chain complex III inhibitor, powder

CHIR99021
SML1046

CHIR99021

≥98% (HPLC), powder, GSK-3 inhibitor

Quercetin
Q4951

Quercetin

≥95% (HPLC), solid, flavonoid antioxidant

Propidium iodide
P4170

Propidium iodide

≥94.0% (HPLC), fluorescent dye, powder

2′,7′-Dichlorodihydrofluorescein diacetate
D6883

2′,7′-Dichlorodihydrofluorescein diacetate

≥97% (HPLC), powder, cell-permeable non-fluorescent probe

Forskolin
F6886

Forskolin

from Coleus forskohlii, ≥98% (HPLC), powder, positive ionotropic agent

3-Isobutyl-1-methylxanthine
I7018

3-Isobutyl-1-methylxanthine

≥99%, Phosphodiesterase inhibitor

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