P2545
Protein A–Agarose
saline suspension
Synonym(s):
Protein A resin
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| Size/SKU | Availability | Price |
|---|---|---|
1 mL | Please contact Customer Service for Availability | €247.00 €209.95 |
5 mL | Please contact Customer Service for Availability | €700.00 €595.00 |
About This Item
Form:
saline suspension
Biological source:
Staphylococcus aureus
€209.95
List Price€247.00Save 15%Web-Only Promotion
Please contact Customer Service for Availability
biological source
Staphylococcus aureus
Quality Segment
form
saline suspension
extent of labeling
~2 mg per mL
matrix activation
cyanogen bromide
matrix attachment
amino
matrix spacer
1 atom
capacity
≥15 mg/mL binding capacity (human IgG)
storage temp.
2-8°C
General description
Protein A is a 42-kDa protein from Staphylococcus aureus and has five immunoglobulin binding domains.[1]
Application
Protein A-agarose is used for affinity chromatography, antibody purification and characterization, and protein A, G and L resins. Protein A-agarose has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer.
Protein A−Agarose has been used in the immunoprecipitation
- of protein phosphatase and tensin homolog (PTEN) protein from S63 and NIH3T3 fibroblast cells
- of prolyl hydroxylase domain 2 N27 cells
- of Wnt3a and sonic hedgehog (Shh) in mouse fibroblast L-cells and human embryonic kidney (HEK) 293 cells
Biochem/physiol Actions
Protein A binds to Fcγ (the constant region) and Fab (antigen binding fragment) of IgG.[1] Protein A agarose resin is commercially used for affinity based purifications.
Physical form
Suspension in 0.5 M NaCl containing preservative
1 of 1
This Item | |||
|---|---|---|---|
| biological source Staphylococcus aureus | biological source - | biological source - | biological source - |
| form saline suspension | form lyophilized powder | form cell suspension | form liquid |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| matrix activation cyanogen bromide | matrix activation cyanogen bromide | matrix activation - | matrix activation - |
| matrix attachment amino | matrix attachment amino | matrix attachment - | matrix attachment - |
| matrix spacer 1 atom | matrix spacer 1 atom | matrix spacer - | matrix spacer - |
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Storage Class
10 - Combustible liquids
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
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