906050
Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide
≥95%
Synonym(s):
Crosslinker−E3 Ligase ligand conjugate, Pomalidomide-6-5-6-I, N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-6-((5-((6-iodohexyl)oxy)pentyl)oxy)hexanamide, Protein degrader building block for PROTAC® research, Template for synthesis of targeted protein degrader
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| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Check Cart for Availability | $582.00 $611.00 |
About This Item
ligand
pomalidomide
assay
≥95%
form
powder or crystals
reaction suitability
reactivity: sulfuryl reactive, reagent type: ligand-linker conjugate
technique(s)
targeted protein degradation: suitable
functional group
alkyl halide
storage temp.
2-8°C
SMILES string
ICCCCCCOCCCCCOCCCCCC(NC1=CC=CC2=C1C(N(C3CCC(NC3=O)=O)C2=O)=O)=O
InChI key
ABEUETLCTXKUSX-UHFFFAOYSA-N
Application
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
Legal Information
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This Item | |||
|---|---|---|---|
| description ≥95% | description ≥95% | description ≥95% | description ≥95% |
| assay ≥95% | assay ≥95% | assay ≥95% | assay ≥95% |
| functional group alkyl halide | functional group alkyl halide | functional group azide | functional group alkyl halide |
| reaction suitability reactivity: sulfuryl reactive, reagent type: ligand-linker conjugate | reaction suitability reagent type: ligand-linker conjugate, reactivity: sulfuryl reactive | reaction suitability reagent type: ligand-linker conjugate, reaction type: click chemistry | reaction suitability reactivity: sulfuryl reactive, reagent type: ligand-linker conjugate |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| form powder or crystals | form powder or crystals | form powder or crystals | form powder or crystals |
| ligand pomalidomide | ligand pomalidomide | ligand pomalidomide | ligand pomalidomide |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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