A7219

Ácido L-aspártico

Name: <SC>Ácido L</SC>-aspártico
Brand: SIGMA

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sinônimo(s):

Ácido (S)-(+)-aminosuccínico, Ácido (S)-aminobutanodioico

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Sobre este item

Fórmula linear:

HO₂CCH₂CH(NH₂)CO₂H

Número CAS:

56-84-8

Peso molecular:

133.10

NACRES:

NA.75

PubChem Substance ID:

24891191

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-291-6

MDL number:

MFCD00002616

Beilstein/REAXYS Number:

1723530

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Nome do produto

Ácido L-aspártico, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

SMILES string

N[C@@H](CC(O)=O)C(O)=O

biological source

non-animal source

agency

meets EP testing specifications
meets USP testing specifications

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

1 M HCl: 100 mg/mL

Quality Level

300

Gene Information

human ... CA1(759), CA2(760)
rat ... Grin2a(24409)

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Categorias relacionadas

Chemistry & Biochemicals

Amino Acids

Biochemicals

Cell Culture Supplements & Reagents

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Este Item	11189	A5474	PHR1104
Sigma-Aldrich A7219 Ácido L-aspártico	Sigma-Aldrich 11189 Ácido L-aspártico	SAFC A5474 Ácido L-aspártico	Supelco PHR1104 Ácido L-aspártico
form powder	form powder or crystals	form crystalline powder	form -
technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
assay 98.5-101.0%	assay ≥99.5% (T)	assay ≥98.5%	assay -
impurities endotoxin, tested	impurities insoluble matter, passes filter test, ≤0.3% foreign amino acids	impurities endotoxin, heavy metals, trace metals, residual solvents, tested	impurities -
solubility 1 M HCl: 100 mg/mL	solubility 1 M HCl: 0.5 M at 20 °C, clear, colorless	solubility 1 M HCl: 50 mg/mL	solubility -
Quality Level 300	Quality Level 200	Quality Level 400	Quality Level 300

Biochem/physiol Actions

Principal neurotransmissor de excitação sináptica rápida.

Application

L-Aspartic acid has been used:

as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats[1]
as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR)[2]
as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines[3]

General description

Aspartic acid(ASP)/aspartate, a non-essential amino acid, is naturally produced by mammals. ASP is one of the 20 building-block amino acids of proteins and has a one letter code, D.[4] L-Aspartic acid can be manufactured industrially by an enzymatic process using the aspartase enzyme.[5]

Classe de armazenamento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number

0000511308

0000501771

0000498259

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Aspartic acid

Johnson EC

reference module in biomedical sciences (2017)

Amino acid production

Eggeling L and Sahm H

Comprehensive Biotechnology (2011)

Identification of Ligand-Receptor Interactions: Ligand Molecular Arrays, SPR and NMR Methodologies.

Christopher J Day et al.

Methods in molecular biology (Clifton, N.J.), 1512, 51-63 (2016-11-26)

Despite many years of research into bacterial chemotaxis, the only well characterized system to date is that of E. coli. Even for E. coli, the direct ligand binding had been fully characterized only for aspartate and serene receptors Tar and

Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.

Hongyu Ding et al.

Science advances, 7(47), eabk1023-eabk1023 (2021-11-18)

[Figure: see text].

Efficient Agrobacterium-mediated Transformation of The Elite-Indica Rice Variety Komboka.

Van T Luu et al.

Bio-protocol, 10(17), e3739-e3739 (2021-03-05)

Genetic transformation is crucial for both investigating gene functions and for engineering of crops to introduce new traits. Rice (Oryza sativa L.) is an important model in plant research, since it is the staple food for more than half of

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Questions

2 years ago

How to solubilize in water?

1 answer
1. Technical Support
  
  2 years ago
  
  L-Aspartic acid is soluble in water at 5 mg/mL.
  
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