R3250 is classified as a matrix dispersion. This product contains gelatin, sugar, modified food starch, and other components to make it convenient as an "oil dispersible material," which will not dissolve in chloroform. The gelatin and starch components in this product would not be soluble but will be dispersed or suspended in the oil. For a soluble retinol acetate product, recommended Product No. is R4632, Retinol Acetate all trans, which is soluble in chloroform (50 mg/ml), yielding a clear, yellow-green solution. Product No. R4632 is also soluble in ethanol.
R3250
Retinil acetato
synthetic, matrix dispersion, 475,000-650,000 USP units/g
Sinonimo/i:
Retinolo acetato, Vitamina A acetato
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10 G
22,95 €
100 G
124,00 €
22,95 €
Prezzo di listino27,00 €Risparmia il 15%Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C22H32O2
Numero CAS:
Peso molecolare:
328.49
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058009
UNSPSC Code:
12352205
EC Number:
204-844-2
MDL number:
Beilstein/REAXYS Number:
1915439
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Permettici di aiutartiNome del prodotto
Retinil acetato, synthetic, matrix dispersion, 475,000-650,000 USP units/g
InChI key
QGNJRVVDBSJHIZ-QHLGVNSISA-N
InChI
1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
SMILES string
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
biological source
synthetic
form
matrix dispersion
specific activity
475,000-650,000 USP units/g
color
yellow
mp
57-58 °C
storage temp.
−20°C
Quality Level
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Categorie correlate
1 of 4
Questo articolo | R7882 | 46958 | R0300000 |
|---|---|---|---|
| biological source synthetic | biological source synthetic | biological source - | biological source synthetic |
| form matrix dispersion | form solid or viscous liquid | form - | form solid |
| storage temp. −20°C | storage temp. −20°C | storage temp. -10 to -25°C | storage temp. −20°C |
| mp 57-58 °C | mp 57-58 °C | mp 57-58 °C | mp 57-58 °C |
| color yellow | color light yellow to dark yellow | color - | color - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level - |
Analysis Note
Activity based on HPLC comparison to USP standard.
Application
Retinyl acetate has been used:
- a control diet to study its effect at different developmental periods in fish larvae[1]
- to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains[2]
- as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk[3]
Biochem/physiol Actions
General description
Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.[4]
Physical form
Dispersion in cornstarch-gelatin matrix. Oil dispersible
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 1B
Classe di stoccaggio
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax)
Villeneuve LAN, et al.
The British Journal of Nutrition, 95(4), 677-687 (2006)
Laure A N Villeneuve et al.
The British journal of nutrition, 95(4), 677-687 (2006-03-31)
The effect of the feeding period on larval development was investigated in European sea bass larvae by considering the expression level of some genes involved in morphogenesis. Larvae were fed a control diet except during three different periods (period A:
Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid
Udeani GO, et al.
Cancer Research, 57(16), 3424-3428 (1997)
Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis
Thompson HJ, et al.
Cancer Research, 41(4), 1413-1416 (1981)
A survey of vitamin A and D contents of fortified fluid milk in Ontario
Faulkner H, et al.
Journal of Dairy Science, 83(6), 1210-1216 (2000)
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What is the solubility information for this product? It is not dissolved in hexane, heptane, acetone, isopropyl alcohol, water, and absolute ethanol; even left overnight on stir plate.
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