R7882

Retinil acetato

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

• Sinonimo/i: Retinolo acetato, Vitamina A acetato
• Formula empirica (notazione di Hill): C₂₂H₃₂O₂
• Numero CAS: 127-47-9
• Peso molecolare: 328.49
• NACRES: NA.75
• PubChem Substance ID: 24899401
• eCl@ss: 34058009
• UNSPSC Code: 12352205
• EC Number: 204-844-2
• MDL number: MFCD00019413
• Beilstein/REAXYS Number: 1915439

Proprietà

• Nome del prodotto: Retinil acetato, solid or viscous liquid, BioReagent, synthetic, suitable for cell culture
• InChI key: QGNJRVVDBSJHIZ-QHLGVNSISA-N
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• SMILES string: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• biological source: synthetic
• product line: BioReagent
• assay: ≥90% (HPLC)
• form: solid or viscous liquid
• potency: ~2,800,000 I.U. per g
• mol wt: M_w 328.49 g/mol
• technique(s): cell culture | mammalian: suitable
• color: light yellow to dark yellow
• mp: 57-58 °C
• solubility: absolute ethanol: 25 mg/mL (lit.)
• storage temp.: −20°C
• Quality Level: 200

Descrizione

Application

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC)[1] and as a supplement in the preparation of the complete medium.[2]

Biochem/physiol Actions

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.[3]

General description

Retinyl-acetate is a natural and ester derivative of vitamin A.[4] It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

Other Notes

All trans

Preparation Note

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

Informazioni sulla sicurezza

• pictograms: GHS08
• signalword: Danger
• hcodes: H360D,H413
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 4 - Repr. 1B
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 2
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter