If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
E6376
エリスロマイシン
potency: ≥850 μg per mg
別名:
Erythromycin A
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製品名
エリスロマイシン, potency: ≥850 μg per mg
InChI key
ULGZDMOVFRHVEP-RWJQBGPGSA-N
InChI
1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
SMILES string
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
biological source
Streptomyces erythreus
form
powder
potency
≥850 μg per mg
color
white
solubility
ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
protein synthesis | interferes
Quality Level
Gene Information
human ... ABCB1(5243), CYP3A4(1576), MLNR(2862)
mouse ... Abcb1a(18671), Abcb1b(18669)
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当該品目 | E0774 | PHR1039 | BP781 |
|---|---|---|---|
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action - | mode of action - |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum - |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level - |
| form powder | form solid | form - | form crystalline |
| biological source Streptomyces erythreus | biological source - | biological source - | biological source - |
| potency ≥850 μg per mg | potency - | potency - | potency - |
Application
エリスロマイシンは、Streptomyces erythreus（放線菌）の特定の株の増殖により産生される抗生物質です。 この製品は、主にエリスロマイシンAと少量のエリスロマイシンBおよびCから構成され、100 mg/Lの濃度での使用が推奨されます。 50～200 mg/Lの濃度が細菌増殖の制御に効果的であることも証明されています。 エリスロマイシンは、in vitroでヒト気道における呼吸器糖抱合体の分泌を遮断するためのモチリン受容体アゴニストとして使用されるほか、プラスミドが除去された組換えLactococcus lactis MG1363株を選択するために使用されています。
Biochem/physiol Actions
抗菌スペクトル：本製品は、グラム陰性細菌とグラム陽性細菌の両方に対して作用します。
Disclaimer
General description
Preparation Note
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
資料
Antibiotics targeting bacterial ribosomes disrupt protein synthesis, a key process in bacterial growth inhibition.
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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