If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf
R3501
リファンピシン
≥95% (HPLC), powder or crystals
別名:
3-(4-メチルピペラジニルイミノメチル)リファマイシンSV, リファマイシンAMP, リファンピン
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About This Item
おすすめの製品
品質水準
アッセイ
≥95% (HPLC)
フォーム
powder or crystals
色
Reddish-brown
pKa
1.7 (4-hydroxyl group)
7.9 (4-piperazine nitrogen)
pI
4.84
抗生物質活性スペクトル
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
viruses
作用機序
protein synthesis | interferes
保管温度
−20°C
SMILES記法
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N5CCN(C)CC5)c(O)c4c3C2=O
InChI
1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
InChI Key
JQXXHWHPUNPDRT-WLSIYKJHSA-N
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詳細
アプリケーション
生物化学的/生理学的作用
その他情報
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral
保管分類コード
11 - Combustible Solids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
R3501-BULK:
R3501-VAR:
R3501-100MG:
R3501-250MG:
R3501-25G:
R3501-5G:
R3501-1G:
最新バージョンのいずれかを選択してください:
試験成績書(COA)
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資料
Discover critical characteristics to consider when working with enzyme inhibitors, such as cell permeability, the prozone effect, and Lipinski’s rule of 5.
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How can I determine the shelf life / expiration / retest date of this product?
1 回答-
役に立ちましたか?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 回答-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
役に立ちましたか?
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What solvent should be used to reconstitute item R3501, Rifampicin?
1 回答-
Rifampicin is soluble in CHCl3. Additionally, it is soluble in water at pH 4.3 (1.3 mg/ml), methanol (25 mg/ml), DMSO (25 mg/ml), dimethyl sulfoxide, tetrahydrofuran, and water at pH 7.3 (2.5 mg/ml at 25°C).
役に立ちましたか?
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What is the difference between the various Rifampicin products available from Sigma-Aldrich?
1 回答-
Sigma-Aldrich offers several Rifampicin products, each tested and best suited for specific applications. The products range from a general use research grade to sterile powder, to plant culture tested. See individual products for specific details.
役に立ちましたか?
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How is the potency determined for Product R3501, Rifampicin?
1 回答-
The potency is determined from a microbiological assay (USP XXII) for antibiotics, a 2-level assay. The test organism is Bacillus subtilis ATCC 6633. The minimum dose is 4.0 μg/ml and the maximum dose is 8.0 μg/ml.
役に立ちましたか?
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The label advises that I should store Product R3501, Rifampicin, frozen. But when it arrived there was no ice in the package. Why is that?
1 回答-
This product in its powder form is stable for short periods of time (i.e., the shipping process), at ambient temperature. For long term storage it is best to store it at -20°C.
役に立ちましたか?
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What is the Department of Transportation shipping information for this product?
1 回答-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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