The primary component of Span 80 is Oleic acid. A number of other fatty acids are also present. While this material is considered a neat or pure product, a molarity cannot be accurately calculated.
09569
Span® 80
suitable for GC
Synonym(s):
Sorbitan monooleate, Span® 80
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50 ML
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About This Item
Empirical Formula (Hill Notation):
C24H44O6
CAS Number:
Molecular Weight:
428.60
Beilstein/REAXYS Number:
8172514
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.21
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description
non-ionic
Quality Level
mol wt
428.60 g/mol
greener alternative product characteristics
Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
LPLC: suitable
gas chromatography (GC): suitable
protein quantification: suitable
refractive index
n20/D 1.48 (lit.)
HLB value
4.6±0.1
density
0.99 g/mL at 20 °C
0.986 g/mL at 25 °C (lit.)
greener alternative category
SMILES string
[H][C@@](O)(COC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O
InChI
1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1
InChI key
NWGKJDSIEKMTRX-AAZCQSIUSA-N
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This Item | 8.40123 | 85548 | S6760 |
|---|---|---|---|
| description non-ionic | description - | description non-ionic | description - |
| mol wt 428.60 g/mol | mol wt - | mol wt 428.60 g/mol | mol wt 428.62 g/mol |
| greener alternative product characteristics Use of Renewable Feedstocks | greener alternative product characteristics Use of Renewable Feedstocks | greener alternative product characteristics Use of Renewable Feedstocks | greener alternative product characteristics - |
| sustainability Greener Alternative Product | sustainability Greener Alternative Product | sustainability Greener Alternative Product | sustainability - |
| technique(s) LPLC: suitable | technique(s) - | technique(s) - | technique(s) - |
| refractive index n20/D 1.48 (lit.) | refractive index - | refractive index n20/D 1.48 (lit.) | refractive index - |
General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is biodegradable surfactant, thus aligns with "Use of Renewable Feedstocks" and "Design for Degradation" principles of Green Chemistry, and belongs to "12 principles aligned" category of our greener alternatives.
Application
A non-ionic surfactant that can be used to form oil-in-water emulsions and in combination with low HLB surfactants can form water-in-oil emulsions. EPA approved oil spill dispersant.
Legal Information
Span is a registered trademark of Croda International PLC
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Faiyaz Shakeel et al.
Drug development and industrial pharmacy, 40(9), 1240-1245 (2013-07-11)
Abstract For the development of an effective self-nanoemulsifying drug delivery system (SNEDDS) of poorly soluble drugs, the knowledge of the solubility in its oil phase and SNEDDS are one of the most important factors to avoid possibility of drug to
Geneviève LeBel et al.
Applied and environmental microbiology, 80(17), 5484-5492 (2014-06-29)
Streptococcus suis serotype 2 is known to cause severe infections (meningitis, endocarditis, and septicemia) in pigs and is considered an emerging zoonotic agent. Antibiotics have long been used in the swine industry for disease treatment/prevention and growth promoters. This pattern
Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 106, 258-264 (2013-02-26)
We have focused on the interaction between the Span 80 vesicle and phospholipid vesicle (liposome). The Span 80 vesicle was mixed with a phospholipid vesicle (liposome), used as a simplified model of plasma membrane. From calcein leakage experiments, it was
Jingchun Zhang et al.
Langmuir : the ACS journal of surfaces and colloids, 28(17), 6769-6775 (2012-04-06)
The effects of salt on emulsions containing sorbitan oleate (Span 80) and Laponite particles were investigated. Surprisingly, a novel double phase inversion was induced by simply changing the salt concentration. At fixed concentration of Laponite particles in the aqueous phase
Keita Hayashi et al.
International journal of biological sciences, 9(2), 142-148 (2013-02-16)
Span 80 (sorbitan monooleate) vesicles behaved differently from conventional phospholipid vesicles (liposomes) because the former had a more fluid interface. After doxorubicin hydrochloride (DOX) was encapsulated into the Span 80 vesicle (loading efficiency: 63 %), DOX-loaded Span 80 vesicles (DVs)
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